Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting.
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Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming.Genome-wide multilocus imprinting disturbance analysis in Temple syndrome and Kagami-Ogata syndromePathogenic variant in NLRP7 (19q13.42) associated with recurrent gestational trophoblastic disease: Data from early embryo development observed during in vitro fertilizationHuman Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting.Epigenetic Characterization of CDKN1C in Placenta Samples from Non-syndromic Intrauterine Growth Restriction.Two novel mutations in the KHDC3L gene in Asian patients with recurrent hydatidiform mole.Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta.Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.Maternal heterozygous NLRP7 variant results in recurrent reproductive failure and imprinting disturbances in the offspring.Recent Advances in Imprinting Disorders.NLRP7 contributes to in vitro decidualization of endometrial stromal cells.Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors.Genomic imprinting, disrupted placental expression, and speciation.Phenotypic spectrum and extent of DNA methylation defects associated with multilocus imprinting disturbances.Maternal variants in NLRP and other maternal effect proteins are associated with multilocus imprinting disturbance in offspring.LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation
P2860
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P2860
Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Absence of Maternal Methylatio ...... Placenta-Specific Imprinting.
@ast
Absence of Maternal Methylatio ...... Placenta-Specific Imprinting.
@en
type
label
Absence of Maternal Methylatio ...... Placenta-Specific Imprinting.
@ast
Absence of Maternal Methylatio ...... Placenta-Specific Imprinting.
@en
prefLabel
Absence of Maternal Methylatio ...... Placenta-Specific Imprinting.
@ast
Absence of Maternal Methylatio ...... Placenta-Specific Imprinting.
@en
P2093
P2860
P50
P1433
P1476
Absence of Maternal Methylatio ...... d Placenta-Specific Imprinting
@en
P2093
Alejandro Martin-Trujillo
Chiharu Tayama
David Monk
Enrique Vidal
Kazuhiko Nakabayashi
Ken Maclean
Kenichiro Hata
Nandita Deo
Olivia Barney
P2860
P304
P356
10.1371/JOURNAL.PGEN.1005644
P577
2015-11-06T00:00:00Z