GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection

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Mammalian Target of Rapamycin Inhibition in Trypanosoma cruzi-Infected Macrophages Leads to an Intracellular Profile That Is Detrimental for Infection.Limited Foxp3 Regulatory T Cells Response During Acute Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8 T Cell Immunity

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GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection

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2017年学术文章

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GRAIL and Otubain-1 are Relate ...... ng Trypanosoma cruzi Infection

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GRAIL and Otubain-1 are Relate ...... ng Trypanosoma cruzi Infection

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Item

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GRAIL and Otubain-1 are Relate ...... ng Trypanosoma cruzi Infection

@ast

GRAIL and Otubain-1 are Relate ...... ng Trypanosoma cruzi Infection

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GRAIL and Otubain-1 are Relate ...... ng Trypanosoma cruzi Infection

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GRAIL and Otubain-1 are Relate ...... ng Trypanosoma cruzi Infection

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P1476

GRAIL and Otubain-1 are Relate ...... ng Trypanosoma cruzi Infection

@en

P2093

Cinthia C Stempin

http://www.w3.org/2001/XMLSchema#string

Jorge D Rojas Marquez

http://www.w3.org/2001/XMLSchema#string

Yamile Ana

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P2860

Otubains: a new family of cysteine proteases in the ubiquitin pathway

Cutting edge: The transmembrane E3 ligase GRAIL ubiquitinates the costimulatory molecule CD40 ligand during the induction of T cell anergy

Mechanisms of Trypanosoma cruzi persistence in Chagas disease

GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells

Two isoforms of otubain 1 regulate T cell anergy via GRAIL

Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease

E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance

Chagas' disease and the autoimmunity hypothesis.

Naive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expression

The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation.

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e0005307

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scholarly article

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10.1371/JOURNAL.PNTD.0005307

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English

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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Fabio M Cerban

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2017-01-23T00:00:00Z

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28114324

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Trypanosoma cruzi

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5289611

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GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection

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P2860

P2860

GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection

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name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932