The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways
about
A conserved biogenesis pathway for nucleoporins: proteolytic processing of a 186-kilodalton precursor generates Nup98 and the novel nucleoporin, Nup96Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export.Association of the human SUMO-1 protease SENP2 with the nuclear poreNucleocytoplasmic transport of proteins and poly(A)+ RNA in reconstituted Tpr-less nuclei in living mammalian cellsLocalization of nucleoporin Tpr to the nuclear pore complex is essential for Tpr mediated regulation of the export of unspliced RNA.GLFG and FxFG nucleoporins bind to overlapping sites on importin-betaSnurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structureThe human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A)+ RNA exportNucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 RevThe Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to humanIdentification of a new vertebrate nucleoporin, Nup188, with the use of a novel organelle trap assayNup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein exportDisruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and functionThe nucleoporin nup153 plays a critical role in multiple types of nuclear exportNpp106p, a Schizosaccharomyces pombe nucleoporin similar to Saccharomyces cerevisiae Nic96p, functionally interacts with Rae1p in mRNA exportRanGTP-mediated nuclear export of karyopherin alpha involves its interaction with the nucleoporin Nup153Cofactor requirements for nuclear export of Rev response element (RRE)- and constitutive transport element (CTE)-containing retroviral RNAs. An unexpected role for actin.Major binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein TprComplex Commingling: Nucleoporins and the Spindle Assembly CheckpointPicornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virusStructural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore ComplexNup116p and nup100p are interchangeable through a conserved motif which constitutes a docking site for the mRNA transport factor gle2p.Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNAThe integral membrane protein snl1p is genetically linked to yeast nuclear pore complex function.The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear importThe role of NUP98 gene fusions in hematologic malignancyNUP98 dysregulation in myeloid leukemogenesisHuman Nup98 regulates the localization and activity of DExH/D-box helicase DHX9The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway.Nup98 is a mobile nucleoporin with transcription-dependent dynamics.The matrix protein of vesicular stomatitis virus inhibits nucleocytoplasmic transport when it is in the nucleus and associated with nuclear pore complexes.The C. elegans homolog of nucleoporin Nup98 is required for the integrity and function of germline P granulesNUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia.Transport of macromolecules between the nucleus and the cytoplasmRNA association defines a functionally conserved domain in the nuclear pore protein Nup153.The molecular mechanism of transport of macromolecules through nuclear pore complexes.Molecular mechanism of translocation through nuclear pore complexes during nuclear protein import.Regulation of mRNA trafficking by nuclear pore complexes.
P2860
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P2860
The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
The vertebrate GLFG nucleopori ...... f multiple RNA export pathways
@ast
The vertebrate GLFG nucleopori ...... f multiple RNA export pathways
@en
type
label
The vertebrate GLFG nucleopori ...... f multiple RNA export pathways
@ast
The vertebrate GLFG nucleopori ...... f multiple RNA export pathways
@en
prefLabel
The vertebrate GLFG nucleopori ...... f multiple RNA export pathways
@ast
The vertebrate GLFG nucleopori ...... f multiple RNA export pathways
@en
P2093
P2860
P356
P1476
The vertebrate GLFG nucleopori ...... f multiple RNA export pathways
@en
P2093
P2860
P304
P356
10.1083/JCB.136.2.241
P407
P577
1997-01-01T00:00:00Z