Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System. - Wikidata - wikimedia - TriplyDB

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

http://www.wikidata.org/entity/Q36259528

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Evolutionary Ecology of Prokaryotic Immune Mechanisms Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli CRISPR-Cas: biology, mechanisms and relevance Spacer-length DNA intermediates are associated with Cas1 in cells undergoing primed CRISPR adaptation.Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity.Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS.Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA Just how Lamarckian is CRISPR-Cas immunity: the continuum of evolvability mechanisms.SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells Highly efficient primed spacer acquisition from targets destroyed by the Escherichia coli type I-E CRISPR-Cas interfering complex The CRISPR RNA-guided surveillance complex in Escherichia coli accommodates extended RNA spacers Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9.DNA Targeting by a Minimal CRISPR RNA-Guided Cascade.CRISPR-Cas: Adapting to change.Conformational regulation of CRISPR-associated nucleases.Active and adaptive Legionella CRISPR-Cas reveals a recurrent challenge to the pathogen.Broad Targeting Specificity during Bacterial Type III CRISPR-Cas Immunity Constrains Viral Escape.High tolerance to self-targeting of the genome by the endogenous CRISPR-Cas system in an archaeon.The Influence of Copy-Number of Targeted Extrachromosomal Genetic Elements on the Outcome of CRISPR-Cas Defense.Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition.Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR-Cas system.Conformational Control of Cascade Interference and Priming Activities in CRISPR Immunity CRISPR-Cas adaptive immunity and the three Rs.Memory Upgrade: Insights into Primed Adaptation by CRISPR-Cas Immune Systems.Visualization of phage DNA degradation by a type I CRISPR-Cas system at the single-cell level.Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade.Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.Utilizing Biotinylated Proteins Expressed in Yeast to Visualize DNA-Protein Interactions at the Single-Molecule Level.The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit.Conformational Dynamics of DNA Binding and Cas3 Recruitment by the CRISPR RNA-Guided Cascade Complex.Mobile Genetic Elements and Evolution of CRISPR-Cas Systems: All the Way There and Back.Priming in a permissive type I-C CRISPR-Cas system reveals distinct dynamics of spacer acquisition and loss.Life under the Microscope: Single-Molecule Fluorescence Highlights the RNA World.Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.Determining the Specificity of Cascade Binding, Interference, and Primed Adaptation In Vivo in the Escherichia coli Type I-E CRISPR-Cas System.Cas4-Dependent Prespacer Processing Ensures High-Fidelity Programming of CRISPR Arrays.Primed CRISPR adaptation in Escherichia coli cells does not depend on conformational changes in the Cascade effector complex detected in Vitro.The CRISPR conundrum: evolve and maybe die, or survive and risk stagnation.

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

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Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

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Bryan Gibb

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Chantal K Guegler

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Eric C Greene

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Myles Marshall

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Samuel H Sternberg

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Sy Redding

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A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product

CRISPR-Cas systems: Prokaryotes upgrade to adaptive immunity

Structural and Biochemical Analysis of Nuclease Domain of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Protein 3 (Cas3)

Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System

Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity

In vivo protein interactions and complex formation in the Pectobacterium atrosepticum subtype I-F CRISPR/Cas System

Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements

Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin

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Jennifer Doudna

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2015-10-28T00:00:00Z

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Escherichia coli

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