Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris.
about
Pemphigus vulgaris antibody identifies pemphaxin. A novel keratinocyte annexin-like molecule binding acetylcholinePerturbed desmosomal cadherin expression in grainy head-like 1-null miceCharacterization of the regulatory regions in the human desmoglein genes encoding the pemphigus foliaceous and pemphigus vulgaris antigensSuprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation.Defining the pathogenic involvement of desmoglein 4 in pemphigus and staphylococcal scalded skin syndromeAssessment of splice variant-specific functions of desmocollin 1 in the skinThe desmosomeA homozygous nonsense mutation in the human desmocollin-3 (DSC3) gene underlies hereditary hypotrichosis and recurrent skin vesiclesNovel human alpha9 acetylcholine receptor regulating keratinocyte adhesion is targeted by Pemphigus vulgaris autoimmunityDesmosomes in acquired diseaseDownregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma developmentDesmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkageA new role for neurotrophin-3: involvement in the regulation of hair follicle regression (catagen)Smad4-dependent desmoglein-4 expression contributes to hair follicle integrityExpression and localization of P-, K-, and OB-cadherin in the prepubertal rat ovaryA role for chromosomal protein HMGN1 in corneal maturationInvolvement of a tissue-specific autoantibody in skin disorders of murine systemic lupus erythematosus and autoinflammatory diseasesLessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope proteinA novel mouse desmosomal cadherin family member, desmoglein 1 gammaShort tail with skin lesion phenotype occurs in transgenic mice with keratin-14 promoter-directed expression of mutant CXCR2.Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanismDesmocollin 3-mediated binding is crucial for keratinocyte cohesion and is impaired in pemphigus.Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposureLoss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depotsDesmoglein 3, via an interaction with E-cadherin, is associated with activation of SrcExplanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris.Adhesion receptors in health and disease.Mouse models for blistering skin disorders.Integrating animal models and in vitro tissue models to elucidate the role of desmosomal proteins in diseases.Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies.Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigusThe biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.Hair on a gene string: recent advances in understanding the molecular genetics of hair loss.Desmosomes: structure and function in normal and diseased epidermis.The genetics of human skin disease.Autoimmunity to desmocollin 3 in pemphigus vulgaris.Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables.Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice.Desmoglein 2 is less important than desmoglein 3 for keratinocyte cohesion.Desmosomal defects in acantholytic squamous cell carcinomas.
P2860
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P2860
Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Targeted disruption of the pem ...... similar to pemphigus vulgaris.
@ast
Targeted disruption of the pem ...... similar to pemphigus vulgaris.
@en
type
label
Targeted disruption of the pem ...... similar to pemphigus vulgaris.
@ast
Targeted disruption of the pem ...... similar to pemphigus vulgaris.
@en
prefLabel
Targeted disruption of the pem ...... similar to pemphigus vulgaris.
@ast
Targeted disruption of the pem ...... similar to pemphigus vulgaris.
@en
P2093
P2860
P356
P1476
Targeted disruption of the pem ...... similar to pemphigus vulgaris.
@en
P2093
D Whitaker-Menezes
G F Murphy
H Ishikawa
J R Stanley
L Pulkkinen
M G Mahoney
P2860
P304
P356
10.1083/JCB.137.5.1091
P407
P577
1997-06-01T00:00:00Z