Stabilizing drug molecules in biological samples.

Stabilizing drug molecules in biological samples.

Item
http://www.wikidata.org/entity/Q36262931
Critical topics in ensuring data quality in bioanalytical LC-MS method development.The pharmacokinetics of glycopyrrolate in Standardbred horses.The bioanalytical challenge of determining unbound concentration and protein binding for drugs.Development and validation of an LC-MS/MS method for simultaneous quantification of levodopa and MD01 in rat plasma and its application to a pharmacokinetic study of mucuna pruriens extract.Factors affecting the stability of drugs and drug metabolites in biological matrices.The use of mass spectrometry to analyze dried blood spots.Heat stabilization of blood spot samples for determination of metabolically unstable drug compounds.Pre-analytic evaluation of volumetric absorptive microsampling and integration in a mass spectrometry-based metabolomics workflow.DBS sampling can be used to stabilize prodrugs in drug discovery rodent studies without the addition of esterase inhibitors.Degradation of zopiclone during storage of spiked and authentic whole blood and matching dried blood spots.Utilization of dried blood spots within drug discovery: modification of a standard DiLab(®) AccuSampler(®) to facilitate automatic dried blood spot sampling.An industry perspective on tiered approach to the investigation of metabolites in drug development.Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry.A feasibility study prior to an international multicentre paediatric study to assess pharmacokinetic/pharmacodynamic sampling and sample preparation procedures, logistics and bioanalysis
P2860

Stabilizing drug molecules in biological samples.

Item
http://www.wikidata.org/entity/Q36262931
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Stabilizing drug molecules in biological samples.
@ast
Stabilizing drug molecules in biological samples.
@en
type
label
Stabilizing drug molecules in biological samples.
@ast
Stabilizing drug molecules in biological samples.
@en
prefLabel
Stabilizing drug molecules in biological samples.
@ast
Stabilizing drug molecules in biological samples.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Stabilizing drug molecules in biological samples.
@en
P2093
P304
P31
P356
10.1097/01.FTD.0000170879.18139.40
P433
P478
P577
P698