The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
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Na(+)/H(+) exchanger 1 directly binds to calcineurin A and activates downstream NFAT signaling, leading to cardiomyocyte hypertrophyTargeting Cancer Metabolism - Revisiting the Warburg EffectsNitric oxide and pH modulation in gynaecological cancerVoltage-gated sodium channels and cancer: is excitability their primary role?Yeast studies reveal moonlighting functions of the ancient actin cytoskeletonCancer cell metabolism: implications for therapeutic targetsTreatment of intermediate stage hepatocellular carcinoma: a review of intrahepatic doxorubicin drug-delivery systemsProtonation and Trapping of a Small pH-Sensitive Near-Infrared Fluorescent Molecule in the Acidic Tumor Environment Delineate Diverse Tumors in Vivo.Calcium signals driven by single channel noiseIon transporters in brain tumorsThe dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunityThe Intercellular Metabolic Interplay between Tumor and Immune CellsExosomes from human colorectal cancer induce a tumor-like behavior in colonic mesenchymal stromal cellsLactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoAThe spatial organization of proton and lactate transport in a rat brain tumorExpression of actin-interacting protein 1 suppresses impaired chemotaxis of Dictyostelium cells lacking the Na+-H+ exchanger NHE1Cancer: fundamentals behind pH targeting and the double-edged approachActive versus passive mechanisms in metastasis: do cancer cells crawl into vessels, or are they pushed?Subcellular Energetics and Metabolism: A Cross-Species Framework.Novel multiarm polyethylene glycol-dihydroartemisinin conjugates enhancing therapeutic efficacy in non-small-cell lung cancer.Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come.Considering protonation as a posttranslational modification regulating protein structure and function.The carbonic anhydrase I locus contains a c-Myb target promoter and modulates differentiation of murine erythroleukemia cells.The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transportersThe NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts.Novel phorbol ester-binding motif mediates hormonal activation of Na+/H+ exchanger.Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair.Upregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H⁺ extrusion, cell migration and survival.Theoretical predictions of lactate and hydrogen ion distributions in tumours.NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity.The genomic analysis of lactic acidosis and acidosis response in human cancersEffects of omeprazole in improving concurrent chemoradiotherapy efficacy in rectal cancerLatent factor analysis to discover pathway-associated putative segmental aneuploidies in human cancers.Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Is there a role for voltage-gated Na+ channels in the aggressiveness of breast cancer?Temperature triggered self-assembly of polypeptides into multivalent spherical micelles.25th anniversary article: interfacing nanoparticles and biology: new strategies for biomedicine.Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release.Role of myoepithelial cells in breast tumor progression.
P2860
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P2860
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
@ast
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
@en
type
label
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
@ast
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
@en
prefLabel
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
@ast
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.
@en
P356
P1476
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis
@en
P2093
Rosa A Cardone
P2888
P304
P356
10.1038/NRC1713
P407
P577
2005-10-01T00:00:00Z