Illegitimate recombination generates a class switch from C mu to C delta in an IgD-secreting plasmacytoma

Illegitimate recombination generates a class switch from C mu to C delta in an IgD-secreting plasmacytoma

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http://www.wikidata.org/entity/Q36264990
Immunoglobulin D switching can occur through homologous recombination in human B cellsCompilation of DNA strand exchange sites for non-homologous recombination in somatic cells.Double isotype production by a neoplastic B cell line. II. Allelically excluded production of mu and gamma 1 heavy chains without CH gene rearrangement.High-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genomeNonhomologous recombination at sites within the mouse JH-C delta locus accompanies C mu deletion and switch to immunoglobulin D secretion.Coexpression of mu and gamma 1 heavy chains can occur by a discontinuous transcription mechanism from the same unrearranged chromosome.Independent immunoglobulin class-switch events occurring in a single myeloma cell lineHuman homologs of TU transposon sequences: polypurine/polypyrimidine sequence elements that can alter DNA conformation in vitro and in vivo.A weakly pathogenic Rauscher spleen focus-forming virus mutant that lacks the carboxyl-terminal membrane anchor of its envelope glycoprotein.A serum heterodimer from hagfish (Eptatretus stoutii) exhibits structural similarity and partial sequence identity with immunoglobulin.The normal counterpart of IgD myeloma cells in germinal center displays extensively mutated IgVH gene, Cmu-Cdelta switch, and lambda light chain expression
P2860

Illegitimate recombination generates a class switch from C mu to C delta in an IgD-secreting plasmacytoma

Item
http://www.wikidata.org/entity/Q36264990
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Illegitimate recombination gen ...... an IgD-secreting plasmacytoma
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Illegitimate recombination gen ...... an IgD-secreting plasmacytoma
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Illegitimate recombination gen ...... an IgD-secreting plasmacytoma
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Illegitimate recombination gen ...... an IgD-secreting plasmacytoma
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Illegitimate recombination gen ...... an IgD-secreting plasmacytoma
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Illegitimate recombination gen ...... an IgD-secreting plasmacytoma
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Illegitimate recombination gen ...... an IgD-secreting plasmacytoma
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932