Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3.
about
Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum.RAB and RHO GTPases regulate intestinal crypt cell homeostasis and enterocyte function.Disrupted apical exocytosis of cargo vesicles causes enteropathy in FHL5 patients with Munc18-2 mutations.Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in neonatal enteropathy.Rabs set the stage for polarity.Regulation of Transporters and Channels by Membrane-Trafficking Complexes in Epithelial Cells.Rab GTPases and their interacting protein partners: Structural insights into Rab functional diversity.Towards understanding microvillus inclusion disease.Identification of intestinal ion transport defects in microvillus inclusion disease.Regulation of podocalyxin trafficking by Rab small GTPases in epithelial cells.New Mouse Models for Microvillus Inclusion Disease (MVID): Where Do the Inclusions Come From and Are They Cause or Consequence?Special delivery to the apical membrane.Abnormal Rab11-Rab8-vesicles cluster in enterocytes of patients with microvillus inclusion disease.Trafficking Ion Transporters to the Apical Membrane of Polarized Intestinal Enterocytes.MYO5B, STX3 and STXBP2 mutations reveal a common disease mechanism that unifies a subset of congenital diarrheal disorders: A mutation update.LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.Kinetic signatures of myosin-5B, the motor involved in microvillus inclusion disease.Intestinal epithelial cell polarity defects in disease: lessons from microvillus inclusion disease.Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in -Deficient Intestinal OrganoidsThe scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations and
P2860
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P2860
Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
Cargo-selective apical exocyto ...... Slp4a, Vamp7, and Syntaxin 3.
@ast
Cargo-selective apical exocyto ...... Slp4a, Vamp7, and Syntaxin 3.
@en
type
label
Cargo-selective apical exocyto ...... Slp4a, Vamp7, and Syntaxin 3.
@ast
Cargo-selective apical exocyto ...... Slp4a, Vamp7, and Syntaxin 3.
@en
prefLabel
Cargo-selective apical exocyto ...... Slp4a, Vamp7, and Syntaxin 3.
@ast
Cargo-selective apical exocyto ...... Slp4a, Vamp7, and Syntaxin 3.
@en
P2093
P2860
P356
P1476
Cargo-selective apical exocyto ...... Slp4a, Vamp7, and Syntaxin 3.
@en
P2093
Andreas R Janecke
Katharina M C Klee
Lukas A Huber
Thomas Müller
P2860
P304
P356
10.1083/JCB.201506112
P407
P577
2015-11-01T00:00:00Z