A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
about
Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrierProgress and perspectives on targeting nanoparticles for brain drug delivery.Active trafficking of alpha 1 antitrypsin across the lung endotheliumBlood brain barrier: An overview on strategies in drug delivery, realistic in vitro modeling and in vivo live trackingRegulation of Ketone Body Metabolism and the Role of PPARαEvolving Drug Delivery Strategies to Overcome the Blood Brain Barrier.Targeting of thyroglobulin to transcytosis following megalin-mediated endocytosis: evidence for a preferential pH-independent pathwayThe expression of native and oxidized LDL receptors in brain microvessels is specifically enhanced by astrocytes-derived soluble factor(s)Cubilin, the endocytic receptor for intrinsic factor-vitamin B(12) complex, mediates high-density lipoprotein holoparticle endocytosisLocalized delivery of low-density lipoprotein docosahexaenoic acid nanoparticles to the rat brain using focused ultrasoundIncreased locomotor activity in mice lacking the low-density lipoprotein receptorDrug delivery to the brain by focused ultrasound induced blood-brain barrier disruption: quantitative evaluation of enhanced permeability of cerebral vasculature using two-photon microscopy.Two-photon fluorescence microscopy study of cerebrovascular dynamics in ultrasound-induced blood-brain barrier opening.Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells.Uptake of apolipoprotein E fragment coupled liposomes by cultured brain microvessel endothelial cells and intact brain capillaries.Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans.Metabolomic Identification in Cerebrospinal Fluid of the Effects of High Dietary Cholesterol in a Rabbit Model of Alzheimer's DiseasePotential Pathways for CNS Drug Delivery Across the Blood-Cerebrospinal Fluid BarrierAmyloid and lipids in the pathology of Alzheimer disease.Nanoparticle and iron chelators as a potential novel Alzheimer therapy.HFE gene variants, iron, and lipids: a novel connection in Alzheimer's diseaseAn in silico model of retinal cholesterol dynamics (RCD model): insights into the pathophysiology of dry AMDAdvances in osmotic opening of the blood-brain barrier to enhance CNS chemotherapy.CNS delivery via adsorptive transcytosis.The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cellsEffects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain.Apolipoprotein E LDL receptor-binding domain-containing high-density lipoprotein: a nanovehicle to transport curcumin, an antioxidant and anti-amyloid bioflavonoid.Setting-up an in vitro model of rat blood-brain barrier (BBB): a focus on BBB impermeability and receptor-mediated transportLDL receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapses.Phosphatidylserine in the brain: metabolism and function.Central nervous system: cholesterol turnover, brain development and neurodegeneration.Transcytosis of plasma macromolecules in endothelial cells: a cell biological survey.LDL and HDL transfer rates across peripheral microvascular endothelium agree with those predicted for passive ultrafiltration in humans.Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged ratCaffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases.Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease.Transcytosis: crossing cellular barriers.Disrupted functional and structural networks in cognitively normal elderly subjects with the APOE ɛ4 allele.Abnormal cholesterol is associated with prefrontal white matter abnormalities among obese adults, a diffusion tensor imaging study
P2860
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P2860
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
@ast
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
@en
type
label
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
@ast
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
@en
prefLabel
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
@ast
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
@en
P2093
P2860
P356
P1476
A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier
@en
P2093
P2860
P304
P356
10.1083/JCB.138.4.877
P407
P577
1997-08-01T00:00:00Z