Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
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Determinants of functional disability in Huntington's disease: role of cognitive and motor dysfunctionMagnetic resonance imaging striatal volumes: a biomarker for clinical trials in Huntington's diseaseSorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's diseaseYoung-onset dementiaGait in Huntington's disease and the stride length-cadence relationshipPhosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington DiseasenNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challengeComplex motor task associated with non-linear BOLD responses in cerebro-cortical areas and cerebellum.Striatal parvalbuminergic neurons are lost in Huntington's disease: implications for dystoniaFoxa1 is essential for development and functional integrity of the subthalamic nucleus.Early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of Huntington's diseaseMapping the order and pattern of brain structural MRI changes using change-point analysis in premanifest Huntington's disease.Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease.MicroRNAs in Neurocognitive Dysfunctions: New Molecular Targets for Pharmacological Treatments?Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease.Microtransplantation of whole ganglionic eminence cells ameliorates motor deficit, enlarges the volume of grafts, and prolongs survival in a rat model of Huntington's disease.Globus pallidus degeneration and clinicopathological features of Huntington disease.Involvement of mGlu5 receptor in 3-nitropropionic acid-induced oxidative stress in rat striatum.Reduced striato-cortical and inhibitory transcallosal connectivity in the motor circuit of Huntington's disease patients.Brain MRI Pattern Recognition Translated to Clinical Scenarios.Age-related decrease of functional connectivity additional to gray matter atrophy in a network for movement initiation
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P2860
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
@ast
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
@en
type
label
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
@ast
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
@en
prefLabel
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
@ast
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
@en
P2093
P2860
P356
P1433
P1476
Striatal neuronal loss correlates with clinical motor impairment in Huntington's disease.
@en
P2093
Adam Rosenblatt
Barbara J Crain
Brent A Orr
Juan C Troncoso
Kari-Elise Codispoti
Olga Pletnikova
Russell L Margolis
Wenzhen Duan
Zhihong Guo
P2860
P304
P356
10.1002/MDS.25159
P407
P577
2012-09-13T00:00:00Z