Carcinoembryonic antigen, a human tumor marker, cooperates with Myc and Bcl-2 in cellular transformation
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The specificity for the differentiation blocking activity of carcinoembryonic antigen resides in its glycophosphatidyl-inositol anchorDeregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiationThe adhesion and differentiation-inhibitory activities of the immunoglobulin superfamily member, carcinoembryonic antigen, can be independently blockedColorectal hyperplasia and dysplasia due to human carcinoembryonic antigen (CEA) family member expression in transgenic mice.Elevated serum CEA levels are associated with the explosive progression of lung adenocarcinoma harboring EGFR mutationsSoluble epidermal growth factor receptor (sEGFR) and carcinoembryonic antigen (CEA) concentration in patients with non-small cell lung cancer: correlation with survival after erlotinib and gefitinib treatment.Evolution of a tumorigenic property conferred by glycophosphatidyl-inositol membrane anchors of carcinoembryonic antigen gene family members during the primate radiation.The molecular mechanisms used by Neisseria gonorrhoeae to initiate infection differ between men and women.Normal carcinoembryonic antigen indicates benefit from perioperative chemotherapy to gastric carcinoma patients.Prognostic and predictive value of carcinoembryonic antigen and cytokeratin-19 fragments levels in advanced non-small cell lung cancer patients treated with gefitinib or erlotinibPrognostic and predictive value of CEA and CYFRA 21-1 levels in advanced non-small cell lung cancer patients treated with gefitinib or erlotinibIdentification of a broad coverage HLA-DR degenerate epitope pool derived from carcinoembryonic antigen.Blocking the attachment of cancer cells in vivo with DNA aptamers displaying anti-adhesive properties against the carcinoembryonic antigen.Constitutively active TrkB confers an aggressive transformed phenotype to a neural crest-derived cell line.Carcinoembryonic antigen interacts with TGF-{beta} receptor and inhibits TGF-{beta} signaling in colorectal cancers.Specific inhibition of GPI-anchored protein function by homing and self-association of specific GPI anchors.Interdependency of CEACAM-1, -3, -6, and -8 induced human neutrophil adhesion to endothelial cells.Bcl-2 and c-Myc co-operate in the Epstein-Barr virus-immortalized human B-cell line GM607 but do not confer tumorigenicity.Two new synthetic peptides from the N-domain of CEACAM1 (CD66a) stimulate neutrophil adhesion to endothelial cells.Prodrug chemotherapeutics bypass p-glycoprotein resistance and kill tumors in vivo with high efficacy and target-dependent selectivity.cea5, a structurally divergent member of the murine carcinoembryonic antigen gene family, is exclusively expressed during early placental development in trophoblast giant cells.The Association of Serum Carcinoembryonic Antigen, Carbohydrate Antigen 19-9, Thymidine Kinase, and Tissue Polypeptide Specific Antigen with Outcomes of Patients with Metastatic Colorectal Cancer Treated with Bevacizumab: a Retrospective Study.The prognosis of gastric cancer patients with marginally elevated carcinoembryonic antigen (CEA) values after D2 radical gastrectomy.Tumor Expression of the Carcinoembryonic Antigen Correlates with High Mitotic Activity and Cell Pleomorphism Index in Lung Carcinoma
P2860
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P2860
Carcinoembryonic antigen, a human tumor marker, cooperates with Myc and Bcl-2 in cellular transformation
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Carcinoembryonic antigen, a hu ...... l-2 in cellular transformation
@ast
Carcinoembryonic antigen, a hu ...... l-2 in cellular transformation
@en
type
label
Carcinoembryonic antigen, a hu ...... l-2 in cellular transformation
@ast
Carcinoembryonic antigen, a hu ...... l-2 in cellular transformation
@en
prefLabel
Carcinoembryonic antigen, a hu ...... l-2 in cellular transformation
@ast
Carcinoembryonic antigen, a hu ...... l-2 in cellular transformation
@en
P2860
P356
P1476
Carcinoembryonic antigen, a hu ...... l-2 in cellular transformation
@en
P2093
C P Stanners
R A Screaton
P2860
P304
P356
10.1083/JCB.137.4.939
P407
P50
P577
1997-05-01T00:00:00Z