Differential sorting of lysosomal enzymes out of the regulated secretory pathway in pancreatic beta-cells
about
P-CIP1, a novel protein that interacts with the cytosolic domain of peptidylglycine alpha-amidating monooxygenase, is associated with endosomesIslet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cellsThe Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granulesVesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle traffickingCathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug CandidateMultiple roles for the actin cytoskeleton during regulated exocytosisThe cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activitySignaling mediated by the cytosolic domain of peptidylglycine alpha-amidating monooxygenaseA subset of p23 localized on secretory granules in pancreatic beta-cellsSynaptotagmin IV is necessary for the maturation of secretory granules in PC12 cellsResting (basal) secretion of proteins is provided by the minor regulated and constitutive-like pathways and not granule exocytosis in parotid acinar cells.Immunoglobulin-derived polypeptides enter the regulated secretory pathway in AtT-20 cells.Comparative pathology of murine mucolipidosis types II and IIICTumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells.Regulated secretion from hemopoietic cells.Chromogranin B (secretogranin I), a neuroendocrine-regulated secretory protein, is sorted to exocrine secretory granules in transgenic miceProinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.Trans-Golgi network sorting.A regulatory pathway, ecdysone-transcription factor relish-cathepsin L, is involved in insect fat body dissociation.Proinsulin endoproteolysis confers enhanced targeting of processed insulin to the regulated secretory pathwayAdventures with insulin in the islets of LangerhansCathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.Not all secretory granules are created equal: Partitioning of soluble content proteins.Cathepsin L and Arg/Lys aminopeptidase: a distinct prohormone processing pathway for the biosynthesis of peptide neurotransmitters and hormones.An Active 32-kDa Cathepsin L Is Secreted Directly from HT 1080 Fibrosarcoma Cells and Not via Lysosomal Exocytosis.Parotid secretory granules: crossroads of secretory pathways and protein storage.Protein sorting to the storage vacuoles of plants: a critical appraisal.Induction of integral membrane PAM expression in AtT-20 cells alters the storage and trafficking of POMC and PC1.Mannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesiclesA phosphorylation site regulates sorting of the vesicular acetylcholine transporter to dense core vesicles.Homotypic fusion of immature secretory granules during maturation in a cell-free assayRegulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-deficient human macrophages.An acidic motif retains vesicular monoamine transporter 2 on large dense core vesicles.Dense-core secretory granule biogenesis.Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cellsLumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell.How peptide hormone vesicles are transported to the secretion site for exocytosis.Homotypic fusion of immature secretory granules during maturation requires syntaxin 6Syntaxin-6 SNARE involvement in secretory and endocytic pathways of cultured pancreatic beta-cells.Architecture of the mammalian Golgi.
P2860
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P2860
Differential sorting of lysosomal enzymes out of the regulated secretory pathway in pancreatic beta-cells
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Differential sorting of lysoso ...... thway in pancreatic beta-cells
@ast
Differential sorting of lysoso ...... thway in pancreatic beta-cells
@en
type
label
Differential sorting of lysoso ...... thway in pancreatic beta-cells
@ast
Differential sorting of lysoso ...... thway in pancreatic beta-cells
@en
prefLabel
Differential sorting of lysoso ...... thway in pancreatic beta-cells
@ast
Differential sorting of lysoso ...... thway in pancreatic beta-cells
@en
P2093
P2860
P356
P1476
Differential sorting of lysoso ...... thway in pancreatic beta-cells
@en
P2093
P2860
P304
P356
10.1083/JCB.137.3.595
P407
P577
1997-05-01T00:00:00Z