Homeobox gene expression in cancer: insights from developmental regulation and deregulation.
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DLX5 (distal-less homeobox 5) promotes tumor cell proliferation by transcriptionally regulating MYCHomeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-β cytostatic program and blocks the antiproliferative effect of TGF-βThe DACH/EYA/SIX gene network and its role in tumor initiation and progressionA reverse transcriptase-dependent mechanism is essential for murine preimplantation developmentCharacterization of the Six1 homeobox gene in normal mammary gland morphogenesis.Ancient genes establish stress-induced mutation as a hallmark of cancerMutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231DNA methylation profiles in ovarian cancer: implication in diagnosis and therapy (Review)HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.HOXA9 promotes homotypic and heterotypic cell interactions that facilitate ovarian cancer dissemination via its induction of P-cadherinHOXA1 is overexpressed in oral squamous cell carcinomas and its expression is correlated with poor prognosis.Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling.HOXB5 expression in oral squamous cell carcinomaGrowth and differentiation factor 3 induces expression of genes related to differentiation in a model of cancer stem cells and protects them from retinoic acid-induced apoptosis.WT1 represses HOX gene expression in the regulation of gynaecologic tumour histologic typeThyroid-specific transcription factors and their roles in thyroid cancer.Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis.Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties.Gene expression differences between colon and rectum tumorsFunctional interaction between the homeoprotein CDX1 and the transcriptional machinery containing the TATA-binding proteinDeregulated HOXB7 Expression Predicts Poor Prognosis of Patients with Esophageal Squamous Cell Carcinoma and Regulates Cancer Cell Proliferation In Vitro and In Vivo.Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival.Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay.HOXA10 controls proliferation, migration and invasion in oral squamous cell carcinoma.A homeobox gene related to Drosophila distal-less promotes ovarian tumorigenicity by inducing expression of vascular endothelial growth factor and fibroblast growth factor-2Smad2/3-Regulated Expression of DLX2 Is Associated with Radiation-Induced Epithelial-Mesenchymal Transition and Radioresistance of A549 and MDA-MB-231 Human Cancer Cell Lines.Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis.HOXA9 promotes ovarian cancer growth by stimulating cancer-associated fibroblasts.Overexpression of HOXB7 is associated with a poor prognosis in patients with gastric cancerElevated HOXA1 expression correlates with accelerated tumor cell proliferation and poor prognosis in gastric cancer partly via cyclin D1Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs.HOXB7 as a promising molecular marker for metastasis in cancers: a meta-analysis.Retrotransposon-encoded reverse transcriptase in the genesis, progression and cellular plasticity of human cancer.Expression profile of SIX family members correlates with clinic-pathological features and prognosis of breast cancer: A systematic review and meta-analysis.Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition.The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signalingHOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma.Expression of the homeobox gene HOXA9 in ovarian cancer induces peritoneal macrophages to acquire an M2 tumor-promoting phenotype.HOXB7 overexpression promotes cell proliferation and correlates with poor prognosis in gastric cancer patients by inducing expression of both AKT and MARKs.Homeobox Gene Deregulation: Impact on the Hallmarks of Cancer
P2860
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P2860
Homeobox gene expression in cancer: insights from developmental regulation and deregulation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Homeobox gene expression in ca ...... l regulation and deregulation.
@ast
Homeobox gene expression in ca ...... l regulation and deregulation.
@en
type
label
Homeobox gene expression in ca ...... l regulation and deregulation.
@ast
Homeobox gene expression in ca ...... l regulation and deregulation.
@en
prefLabel
Homeobox gene expression in ca ...... l regulation and deregulation.
@ast
Homeobox gene expression in ca ...... l regulation and deregulation.
@en
P1476
Homeobox gene expression in ca ...... l regulation and deregulation.
@en
P2093
Honami Naora
Shaija Samuel
P304
P356
10.1016/J.EJCA.2005.08.014
P577
2005-09-30T00:00:00Z