Targeted overexpression of Dkk1 in osteoblasts reduces bone mass but does not impair the anabolic response to intermittent PTH treatment in mice.
about
Intermittent parathyroid hormone (PTH) promotes cementogenesis and alleviates the catabolic effects of mechanical strain in cementoblasts.Parathyroid hormone: anabolic and catabolic actions on the skeletonWnts' fashion statement: from body stature to dysplasia.Consequences of daily administered parathyroid hormone on myeloma growth, bone disease, and molecular profiling of whole myelomatous bone.Loss of Gsα early in the osteoblast lineage favors adipogenic differentiation of mesenchymal progenitors and committed osteoblast precursors.Scavenger receptor class B, type I (Scarb1) deficiency promotes osteoblastogenesis but stunts terminal osteocyte differentiation.Anabolic and catabolic regimens of human parathyroid hormone 1-34 elicit bone- and envelope-specific attenuation of skeletal effects in Sost-deficient mice.Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.Anti-DKK1 antibody promotes bone fracture healing through activation of β-catenin signaling.Selective deletion of the membrane-bound colony stimulating factor 1 isoform leads to high bone mass but does not protect against estrogen-deficiency bone loss.A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.A DNA binding mutation in estrogen receptor-α leads to suppression of Wnt signaling via β-catenin destabilization in osteoblasts.Role of fibroblast growth factor 2 and Wnt signaling in anabolic effects of parathyroid hormone on bone formation.Update on Wnt signaling in bone cell biology and bone disease.Defective cancellous bone structure and abnormal response to PTH in cortical bone of mice lacking Cx43 cytoplasmic C-terminus domain.Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes.Fibroblast Growth Factor Receptor 3 Deficiency Does Not Impair the Osteoanabolic Action of Parathyroid Hormone on Mice.P2X7 nucleotide receptor signaling potentiates the Wnt/β-catenin pathway in cells of the osteoblast lineageParathyroid hormone 1-34 and skeletal anabolic action: The use of parathyroid hormone in bone formation.Wnt and the Wnt signaling pathway in bone development and disease.From skeletal to cardiovascular disease in 12 steps-the evolution of sclerostin as a major player in CKD-MBD.The osteocyte plays multiple roles in bone remodeling and mineral homeostasis.Wnt/β-catenin signaling mediates osteoblast differentiation triggered by peptide-induced α5β1 integrin priming in mesenchymal skeletal cells.One Year of Abaloparatide, a Selective Activator of the PTH1 Receptor, Increased Bone Formation and Bone Mass in Osteopenic Ovariectomized Rats Without Increasing Bone Resorption.The Load-Bearing Mechanosome Revisited.Homozygous Dkk1 Knockout Mice Exhibit High Bone Mass Phenotype Due to Increased Bone Formation.Cancer Metastases to Bone: Concepts, Mechanisms, and Interactions with Bone Osteoblasts.
P2860
Q33582160-D7A01DFC-CA05-4B17-96E6-D5989CC23004Q33609126-9434D92C-D3B7-4004-A8D2-C56AEF7568B2Q33833409-FEB2FF28-F4C8-4948-AE78-4BEB3798AE1BQ34418934-1E790604-A3A1-4906-9BA3-77447758F989Q34454025-5541C458-DC30-4E97-AE43-E0F47D1CBABAQ34622857-D8E75C37-CA53-4ECE-9E6F-5035CABC90B9Q35110851-61BA3B48-3B97-4FCF-A1E2-910966E34D00Q35187105-A3AD8E45-5894-4E9D-9974-53898E5C8D2EQ35224081-41DB38C8-4407-49B9-822B-66E74B2FB515Q35230310-AD90129E-F93D-434B-8E33-D3383B1D7FE3Q35755034-D92E1891-972F-4BCC-B6D5-53B92CA8A29DQ35952286-5D1FA814-DA13-41A2-B5E8-319867629770Q36020434-95267E68-5FFE-47CB-9757-812DDD3B644CQ36083303-E346D0C9-FC4A-4862-B5BA-1FEFDBE5062CQ36269032-3E5BC797-2E53-4BB2-A348-78C321E5F42CQ36508871-B5A4B7AB-44BC-4F05-9CC1-AC7B4F539B5BQ37148561-EB279C6D-4759-4F55-B394-5B0454A7330BQ37256432-424C578B-723A-41B9-8521-135592817556Q37580945-6AF45E1F-B99E-41C3-BA9F-FD1A474EEE97Q37724188-1E3437E4-F263-4EB0-9B62-A83CDF5D61BDQ38367220-F2B0F77A-B457-4520-905F-43B64B8059FAQ38384295-0504CA91-C308-4027-9ED7-7A1B868C7D64Q38915530-415F09A0-512B-49CE-B0C6-3540CD6CB083Q39283452-DAB621E1-70EC-4E28-842C-3AFC0E8BFEA6Q42711137-703AA713-EBC0-4190-A058-A7F7EC8851E4Q50145648-ADA95B0A-0C79-4EA2-9219-29AD63CE1E14Q55474543-7CD6C4CB-F826-4F75-B884-90E90FB24119
P2860
Targeted overexpression of Dkk1 in osteoblasts reduces bone mass but does not impair the anabolic response to intermittent PTH treatment in mice.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Targeted overexpression of Dkk ...... mittent PTH treatment in mice.
@ast
Targeted overexpression of Dkk ...... mittent PTH treatment in mice.
@en
type
label
Targeted overexpression of Dkk ...... mittent PTH treatment in mice.
@ast
Targeted overexpression of Dkk ...... mittent PTH treatment in mice.
@en
prefLabel
Targeted overexpression of Dkk ...... mittent PTH treatment in mice.
@ast
Targeted overexpression of Dkk ...... mittent PTH treatment in mice.
@en
P2093
P2860
P1476
Targeted overexpression of Dkk ...... mittent PTH treatment in mice.
@en
P2093
Gang-Qing Yao
Jian-Jun Wu
Karl Insogna
Nancy Troiano
P2860
P2888
P304
P356
10.1007/S00774-010-0202-3
P577
2010-07-03T00:00:00Z