Role of genes linked to sporadic Alzheimer's disease risk in the production of β-amyloid peptides
about
Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and TreatmentAdditional mechanisms conferring genetic susceptibility to Alzheimer's diseaseMedial temporal atrophy in early and late-onset Alzheimer's disease.Advances with RNA interference in Alzheimer's disease research.Moving beyond anti-amyloid therapy for the prevention and treatment of Alzheimer's disease.Prediction of disease genes using tissue-specified gene-gene networkCandidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's diseaseATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing.Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tractsA function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer's disease Aβ production.Molecular basis of etiological implications in Alzheimer's disease: focus on neuroinflammation.Dissecting Complex and Multifactorial Nature of Alzheimer's Disease Pathogenesis: a Clinical, Genomic, and Systems Biology Perspective.TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss.Limitations of the hCMEC/D3 cell line as a model for Aβ clearance by the human blood-brain barrier.Chronic Sleep Restriction Induces Cognitive Deficits and Cortical Beta-Amyloid Deposition in Mice via BACE1-Antisense Activation.Bin1 and CD2AP polarise the endocytic generation of beta-amyloid.BIN1 regulates BACE1 intracellular trafficking and amyloid-β production.Bridging Integrator 1 (BIN1) Genotypes Mediate Alzheimer's Disease Risk by Altering Neuronal Degeneration.Using High-Throughput Animal or Cell-Based Models to Functionally Characterize GWAS Signals
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P2860
Role of genes linked to sporadic Alzheimer's disease risk in the production of β-amyloid peptides
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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name
Role of genes linked to sporad ...... oduction of β-amyloid peptides
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Role of genes linked to sporad ...... oduction of β-amyloid peptides
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type
label
Role of genes linked to sporad ...... oduction of β-amyloid peptides
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Role of genes linked to sporad ...... oduction of β-amyloid peptides
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prefLabel
Role of genes linked to sporad ...... oduction of β-amyloid peptides
@ast
Role of genes linked to sporad ...... oduction of β-amyloid peptides
@en
P2860
P356
P1476
Role of genes linked to sporad ...... oduction of β-amyloid peptides
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P2093
Jitin Bali
Sebastian Zurbriggen
P2860
P304
15307-15311
P356
10.1073/PNAS.1201632109
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P577
2012-09-04T00:00:00Z