BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
about
MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL.How to unleash mitochondrial apoptotic blockades to kill cancers?Complementary dynamic BH3 profiles predict co-operativity between the multi-kinase inhibitor TG02 and the BH3 mimetic ABT-199 in acute myeloid leukaemia cellsEpigenetic Treatment of Neurodegenerative Disorders: Alzheimer and Parkinson Diseases.A possible role of GDDR in the development of Helicobacter pylori-associated gastric cancer.Bcl-2 delays cell cycle through mitochondrial ATP and ROS.The potential combination of BCL-2 inhibitors and ibrutinib as frontline therapy in chronic lymphocytic leukemia.Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma.Autophagy, Metabolism, and Cancer.
P2860
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P2860
BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
description
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name
BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
@ast
BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
@en
type
label
BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
@ast
BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
@en
prefLabel
BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
@ast
BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
@en
P2860
P1476
BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis.
@en
P2093
Christopher J Gibson
Matthew S Davids
P2860
P304
P356
10.1158/1078-0432.CCR-15-0364
P407
P577
2015-11-01T00:00:00Z