Novel insight into mechanisms of cholestatic liver injury. - Wikidata - wikimedia - TriplyDB

Novel insight into mechanisms of cholestatic liver injury.

Novel insight into mechanisms of cholestatic liver injury.

http://www.wikidata.org/entity/Q36285749

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Sterile inflammation in acute liver injury: myth or mystery?Xenobiotic and Endobiotic Mediated Interactions Between the Cytochrome P450 System and the Inflammatory Response in the Liver Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse.Adverse Outcome Pathways as Tools to Assess Drug-Induced Toxicity.Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice The Impact of Sterile Inflammation in Acute Liver Injury.Dysregulated hepatic bile acids collaboratively promote liver carcinogenesis.Sandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity.Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patients Protein kinase Cδ protects against bile acid apoptosis by suppressing proapoptotic JNK and BIM pathways in human and rat hepatocytes.Cholestasis induces reversible accumulation of periplakin in mouse liver.Serum metabolic signatures of primary biliary cirrhosis and primary sclerosing cholangitis.Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.CCN1 induces hepatic ductular reaction through integrin αvβ₅-mediated activation of NF-κB.T-helper 17-related cytokines and IgE antibodies during hepatitis A virus infection in children Na(+) /H(+) exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury Molecular adsorbent recirculating system and single-pass albumin dialysis in liver failure--a prospective, randomised crossover study A metabolomic perspective of griseofulvin-induced liver injury in mice.Critical review of resveratrol in xenobiotic-induced hepatotoxicity.Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes Therapeutic targets for cholestatic liver injury Immunological basis in the pathogenesis of intrahepatic cholestasis of pregnancy.Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.Curcumin protects ANIT-induced cholestasis through signaling pathway of FXR-regulated bile acid and inflammation.Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice Role of hemostatic factors in hepatic injury and disease: animal models de-liver.Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.Environmental Xenoestrogens Super-Activate a Variant Murine ER Beta in Cholangiocytes.Development of blood biomarkers for drug-induced liver injury: an evaluation of their potential for risk assessment and diagnostics.Adverse Outcome Pathways and Drug-Induced Liver Injury Testing.Studies on the mechanisms of bile acid initiated hepatic inflammation in cholestatic liver injury.Role of matrix metalloproteinases in cholestasis and hepatic ischemia/reperfusion injury: A review.Functional Immune Anatomy of the Liver-As an Allograft.Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity.Elevated cholesterol levels have a poor prognosis in a cholestasis scenario.Role of the inflammasome in acetaminophen-induced liver injury and acute liver failure.Plasma metabolic profiling of dairy cows affected with clinical ketosis using LC/MS technology.Deregulated neddylation in liver fibrosis.Conjugated bilirubin affects cytokine profiles in hepatitis A virus infection by modulating function of signal transducer and activator of transcription factors.Biliary epithelial injury-induced regenerative response by IL-33 promotes cholangiocarcinogenesis from peribiliary glands.

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Novel insight into mechanisms of cholestatic liver injury.

http://www.wikidata.org/entity/Q36285749

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2012 nî lūn-bûn

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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Novel insight into mechanisms of cholestatic liver injury.

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Novel insight into mechanisms of cholestatic liver injury.

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Novel insight into mechanisms of cholestatic liver injury.

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World Journal of Gastroenterology

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Novel insight into mechanisms of cholestatic liver injury.

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Benjamin L Woolbright

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Hartmut Jaeschke

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P2860

Identification of a nuclear receptor for bile acids

Bile acids: natural ligands for an orphan nuclear receptor

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. UDCA-PBC Study Group

LXRS and FXR: the yin and yang of cholesterol and fat metabolism

In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note

NF-kappaB is activated in cholestasis and functions to reduce liver injury

Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

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