An archaeal immune system can detect multiple protospacer adjacent motifs (PAMs) to target invader DNA.
about
RNA-guided editing of bacterial genomes using CRISPR-Cas systemsProtospacer recognition motifs: mixed identities and functional diversityBiogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunityMolecular mechanisms of CRISPR-mediated microbial immunityGenome-wide identification of transcriptional start sites in the haloarchaeon Haloferax volcanii based on differential RNA-Seq (dRNA-Seq)DNA binding specificities of Escherichia coli Cas1-Cas2 integrase drive its recruitment at the CRISPR locusHaloarcula hispanica CRISPR authenticates PAM of a target sequence to prime discriminative adaptation.Dealing with the evolutionary downside of CRISPR immunity: bacteria and beneficial plasmids.The role of Cas8 in type I CRISPR interference.A novel interference mechanism by a type IIIB CRISPR-Cmr module in Sulfolobus.CRISPR interference (CRISPRi) for sequence-specific control of gene expression.CRISPR-based technologies: prokaryotic defense weapons repurposedTarget motifs affecting natural immunity by a constitutive CRISPR-Cas system in Escherichia coli.COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target SitesViruses of haloarchaea.Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition.CRISPR-Cas immunity against phages: its effects on the evolution and survival of bacterial pathogens.Motif depletion in bacteriophages infecting hosts with CRISPR systemsComparative genomics highlights the unique biology of Methanomassiliicoccales, a Thermoplasmatales-related seventh order of methanogenic archaea that encodes pyrrolysine.CRISPR-Cas Adaptive Immune Systems of the Sulfolobales: Unravelling Their Complexity and Diversity.Archaeal extrachromosomal genetic elementsThree CRISPR-Cas immune effector complexes coexist in Pyrococcus furiosus.Single cells within the Puerto Rico trench suggest hadal adaptation of microbial lineages.DNA targeting by the type I-G and type I-A CRISPR-Cas systems of Pyrococcus furiosus.Characterization of CRISPR RNA biogenesis and Cas6 cleavage-mediated inhibition of a provirus in the haloarchaeon Haloferax mediterranei.Bipartite recognition of target RNAs activates DNA cleavage by the Type III-B CRISPR-Cas systemMetagenomic Analysis of Bacterial Communities of Antarctic Surface Snow.Characterization of eukaryotic microbial diversity in hypersaline Lake Tyrrell, AustraliaCRISPRTarget: bioinformatic prediction and analysis of crRNA targets.Programmable plasmid interference by the CRISPR-Cas system in Thermococcus kodakarensisEvolutionary dynamics of the prokaryotic adaptive immunity system CRISPR-Cas in an explicit ecological contextAdaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming processExploiting CRISPR/Cas: interference mechanisms and applications.The Adaptive Immune System of Haloferax volcanii.DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes.Harnessing Type I and Type III CRISPR-Cas systems for genome editing.CRISPR-mediated targeted mRNA degradation in the archaeon Sulfolobus solfataricus.In vitro assembly and activity of an archaeal CRISPR-Cas type I-A Cascade interference complex.High tolerance to self-targeting of the genome by the endogenous CRISPR-Cas system in an archaeon.Complete genome sequence of 'Halanaeroarchaeum sulfurireducens' M27-SA2, a sulfur-reducing and acetate-oxidizing haloarchaeon from the deep-sea hypersaline anoxic lake Medee.
P2860
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P2860
An archaeal immune system can detect multiple protospacer adjacent motifs (PAMs) to target invader DNA.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
An archaeal immune system can ...... (PAMs) to target invader DNA.
@ast
An archaeal immune system can ...... (PAMs) to target invader DNA.
@en
type
label
An archaeal immune system can ...... (PAMs) to target invader DNA.
@ast
An archaeal immune system can ...... (PAMs) to target invader DNA.
@en
prefLabel
An archaeal immune system can ...... (PAMs) to target invader DNA.
@ast
An archaeal immune system can ...... (PAMs) to target invader DNA.
@en
P2093
P2860
P356
P1476
An archaeal immune system can ...... (PAMs) to target invader DNA.
@en
P2093
Anita Marchfelder
Britta Stoll
Eike Fischer
Friedhelm Pfeiffer
Jutta Brendel
Lisa-Katharina Maier
Mike Dyall-Smith
Susan Fischer
P2860
P304
33351-33363
P356
10.1074/JBC.M112.377002
P407
P577
2012-07-05T00:00:00Z