Inhibition of the angiopoietin/Tie2 axis induces immunogenic modulation, which sensitizes human tumor cells to immune attack.
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Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages.Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival.The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment.Pediatric Phase I Trial and Pharmacokinetic Study of Trebananib in Relapsed Solid Tumors, Including Primary Tumors of the Central Nervous System ADVL1115: A Children's Oncology Group Phase I Consortium Report.
P2860
Inhibition of the angiopoietin/Tie2 axis induces immunogenic modulation, which sensitizes human tumor cells to immune attack.
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Inhibition of the angiopoietin ...... tumor cells to immune attack.
@ast
Inhibition of the angiopoietin ...... tumor cells to immune attack.
@en
type
label
Inhibition of the angiopoietin ...... tumor cells to immune attack.
@ast
Inhibition of the angiopoietin ...... tumor cells to immune attack.
@en
prefLabel
Inhibition of the angiopoietin ...... tumor cells to immune attack.
@ast
Inhibition of the angiopoietin ...... tumor cells to immune attack.
@en
P2093
P2860
P1476
Inhibition of the angiopoietin ...... tumor cells to immune attack.
@en
P2093
Anna R Kwilas
Italia Grenga
James W Hodge
Renee N Donahue
P2860
P2888
P356
10.1186/S40425-015-0096-7
P577
2015-11-17T00:00:00Z