Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells
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Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoirEradication of HIV from Tissue Reservoirs: Challenges for the Cure.In Vivo Suppression of HIV Rebound by Didehydro-Cortistatin A, a "Block-and-Lock" Strategy for HIV-1 Treatment.What do we measure when we measure cell-associated HIV RNA.HIV evolution and diversity in ART-treated patients.Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells.No evidence of ongoing evolution in replication competent latent HIV-1 in a patient followed up for two years.Myeloid Dendritic Cells Induce HIV Latency in Proliferating CD4 T Cells
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P2860
Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells
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Ex vivo activation of CD4+ T-c ...... rom a subset of infected cells
@ast
Ex vivo activation of CD4+ T-c ...... rom a subset of infected cells
@en
type
label
Ex vivo activation of CD4+ T-c ...... rom a subset of infected cells
@ast
Ex vivo activation of CD4+ T-c ...... rom a subset of infected cells
@en
prefLabel
Ex vivo activation of CD4+ T-c ...... rom a subset of infected cells
@ast
Ex vivo activation of CD4+ T-c ...... rom a subset of infected cells
@en
P2093
P2860
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Ex vivo activation of CD4+ T-c ...... rom a subset of infected cells
@en
P2093
Brian Luke
Elizabeth Fyne
Feiyu F Hong
John W Mellors
Michele D Sobolewski
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P304
P356
10.1371/JOURNAL.PPAT.1006230
P577
2017-02-22T00:00:00Z