A conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans.
about
A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreadingThe LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cellsGERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiationA novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interactionA gene expression fingerprint of C. elegans embryonic motor neuronsAn integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegansA novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegansSolution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domainPINCH: More than just an adaptor protein in cellular response.Caenorhabditis elegans beta-G spectrin is dispensable for establishment of epithelial polarity, but essential for muscular and neuronal functionCharacterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migrationMolecular dissection of PINCH-1 reveals a mechanism of coupling and uncoupling of cell shape modulation and survivalTargeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethalityPINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytesSuppressor mutations suggest a surface on PAT-4 (Integrin-linked Kinase) that interacts with UNC-112 (Kindlin).Inhibition of touch cell fate by egl-44 and egl-46 in C. elegansModulation of C. elegans touch sensitivity is integrated at multiple levels.The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!Forces applied during classical touch assays for Caenorhabditis elegansNeural crest cell-specific deletion of Rac1 results in defective cell-matrix interactions and severe craniofacial and cardiovascular malformationsParticularly interesting new cysteine-histidine rich protein expression in colorectal adenocarcinomas.Molecular structure of sarcomere-to-membrane attachment at M-Lines in C. elegans muscleBLMP-1/Blimp-1 regulates the spatiotemporal cell migration pattern in C. elegans.Impact of PINCH expression on survival in colorectal cancer patients.Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscleTopological cluster analysis reveals the systemic organization of the Caenorhabditis elegans connectome.Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell deathIdentification of neuropeptide-like protein gene families in Caenorhabditiselegans and other species.Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization.Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexesDeficiencies in C20 polyunsaturated fatty acids cause behavioral and developmental defects in Caenorhabditis elegans fat-3 mutants.Caenorhabditis elegans UNC-96 is a new component of M-lines that interacts with UNC-98 and paramyosin and is required in adult muscle for assembly and/or maintenance of thick filaments.The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viabilityClinicopathological significance of stromal variables: angiogenesis, lymphangiogenesis, inflammatory infiltration, MMP and PINCH in colorectal carcinomas.Identification of nonviable genes affecting touch sensitivity in Caenorhabditis elegans using neuronally enhanced feeding RNA interference.The DEG/ENaC protein MEC-10 regulates the transduction channel complex in Caenorhabditis elegans touch receptor neuronsThe integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans.A decline in transcript abundance for Heterodera glycines homologs of Caenorhabditis elegans uncoordinated genes accompanies its sedentary parasitic phaseCaenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.
P2860
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P2860
A conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
A conserved LIM protein that a ...... ion in Caenorhabditis elegans.
@ast
A conserved LIM protein that a ...... ion in Caenorhabditis elegans.
@en
type
label
A conserved LIM protein that a ...... ion in Caenorhabditis elegans.
@ast
A conserved LIM protein that a ...... ion in Caenorhabditis elegans.
@en
prefLabel
A conserved LIM protein that a ...... ion in Caenorhabditis elegans.
@ast
A conserved LIM protein that a ...... ion in Caenorhabditis elegans.
@en
P2093
P2860
P356
P1476
A conserved LIM protein that a ...... ion in Caenorhabditis elegans.
@en
P2093
D G Moerman
M C Beckerle
P2860
P356
10.1083/JCB.144.1.45
P407
P577
1999-01-01T00:00:00Z