The unfolded protein response is activated in connexin 50 mutant mouse lenses.
about
Connexin46fs380 causes progressive cataracts.Focus on lens connexins.Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataractConnexin mutants and cataractsHuman βA3/A1-crystallin splicing mutation causes cataracts by activating the unfolded protein response and inducing apoptosis in differentiating lens fiber cellsConnexin50D47A decreases levels of fiber cell connexins and impairs lens fiber cell differentiation.Mechanisms linking connexin mutations to human diseases.Mutations and mechanisms in congenital and age-related cataracts.Lens ER-stress response during cataract development in Mip-mutant mice.The Cataract-linked Mutant Connexin50D47A Causes Endoplasmic Reticulum Stress in Mouse Lenses.Two novel mutations identified in ADCC families impair crystallin protein distribution and induce apoptosis in human lens epithelial cells.Connexins: Synthesis, Post-Translational Modifications, and Trafficking in Health and Disease.
P2860
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P2860
The unfolded protein response is activated in connexin 50 mutant mouse lenses.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
The unfolded protein response is activated in connexin 50 mutant mouse lenses.
@ast
The unfolded protein response is activated in connexin 50 mutant mouse lenses.
@en
type
label
The unfolded protein response is activated in connexin 50 mutant mouse lenses.
@ast
The unfolded protein response is activated in connexin 50 mutant mouse lenses.
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prefLabel
The unfolded protein response is activated in connexin 50 mutant mouse lenses.
@ast
The unfolded protein response is activated in connexin 50 mutant mouse lenses.
@en
P2093
P2860
P1476
The unfolded protein response is activated in connexin 50 mutant mouse lenses
@en
P2093
Bhagwat V Alapure
Jaime K Stull
Zeynep Firtina
P2860
P356
10.1016/J.EXER.2012.06.004
P577
2012-06-17T00:00:00Z