Redundant and unique roles of retinol dehydrogenases in the mouse retina.
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Retinopathy in mice induced by disrupted all-trans-retinal clearanceRod and cone visual pigments and phototransduction through pharmacological, genetic, and physiological approachesRetinol Dehydrogenases Regulate Vitamin A Metabolism for Visual FunctionChemistry of the retinoid (visual) cycleChemistry and biology of the initial steps in vision: the Friedenwald lecture.Phenotype-genotype correlation with Sanger sequencing identified retinol dehydrogenase 12 (RDH12) compound heterozygous variants in a Chinese family with Leber congenital amaurosis.All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis.Fatty acid transport protein 1 regulates retinoid metabolism and photoreceptor development in mouse retina.Retinol dehydrogenase 12 detoxifies 4-hydroxynonenal in photoreceptor cells.Effects of organic solvents on two retinal pigment epithelial lipofuscin fluorophores, A2E and all-trans-retinal dimerThe biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision.Enzymatic degradation of A2E, a retinal pigment epithelial lipofuscin bisretinoid.Pharmacological inhibition of lipofuscin accumulation in the retina as a therapeutic strategy for dry AMD treatment.The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease.Interpretations of fundus autofluorescence from studies of the bisretinoids of the retinaRetinal degeneration in animal models with a defective visual cycle.Fundus autofluorescence and photoreceptor cell rosettes in mouse models.Vitamin A metabolism: an update.Key enzymes of the retinoid (visual) cycle in vertebrate retinaFundus Autofluorescence and RPE Lipofuscin in Age-Related Macular DegenerationSponge transgenic mouse model reveals important roles for the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors of the retina.Evolution of retinoid and steroid signaling: vertebrate diversification from an amphioxus perspective.Targeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory.Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4RDH12 retinopathy: novel mutations and phenotypic description.Metabolism of carotenoids and retinoids related to vision.The Drosophila visual cycle and de novo chromophore synthesis depends on rdhB.Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies.Reduction of all-trans-retinal in vertebrate rod photoreceptors requires the combined action of RDH8 and RDH12.Inflammatory priming predisposes mice to age-related retinal degeneration.Serum levels of lipid metabolites in age-related macular degeneration.Primary amines protect against retinal degeneration in mouse models of retinopathies.Trafficking of membrane-associated proteins to cone photoreceptor outer segments requires the chromophore 11-cis-retinalHighly efficient retinal metabolism in conesInvolvement of all-trans-retinal in acute light-induced retinopathy of mice.Loss of cone photoreceptors caused by chromophore depletion is partially prevented by the artificial chromophore pro-drug, 9-cis-retinyl acetate.Rdh12 activity and effects on retinoid processing in the murine retina.Evaluation of potential therapies for a mouse model of human age-related macular degeneration caused by delayed all-trans-retinal clearanceRetinoids and Retinal Diseases.Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina.
P2860
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P2860
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
@ast
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
@en
type
label
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
@ast
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
@en
prefLabel
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
@ast
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
@en
P2093
P2860
P356
P1476
Redundant and unique roles of retinol dehydrogenases in the mouse retina.
@en
P2093
Akiko Maeda
Houbin Zhang
Tadao Maeda
Wolfgang Baehr
P2860
P304
19565-19570
P356
10.1073/PNAS.0707477104
P407
P577
2007-11-28T00:00:00Z