Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families - Wikidata - wikimedia - TriplyDB

Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

http://www.wikidata.org/entity/Q36292945

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Li-fraumeni syndrome Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype.Inhibition of stress-inducible kinase pathways by tumorigenic mutant p53.Primed for cancer: Li Fraumeni Syndrome and the pre-cancerous niche Malignant transformation and new primary tumours after therapeutic radiation for benign disease: substantial risks in certain tumour prone syndromes Radiation-induced G1 arrest is not defective in fibroblasts from Li-Fraumeni families without TP53 mutations.p53 modulation of the DNA damage response.Genomic alterations associated with loss of heterozygosity for TP53 in Li-Fraumeni syndrome fibroblasts.The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63 Chromosome instability and deregulated proliferation: an unavoidable duo.Antioxidant agents transiently inhibit aneuploidy progression in Li-Fraumeni cell strains.Characterization of germline TP53 splicing mutations and their genetic and functional analysis.The relationship between radiation-induced G(1)arrest and chromosome aberrations in Li-Fraumeni fibroblasts with or without germline TP53 mutations.

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Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

http://www.wikidata.org/entity/Q36292945

description

1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年學術文章

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1998年學術文章

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1998年學術文章

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Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

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Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

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Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

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Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

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Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

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Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

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Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families

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Birch JM

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P2860

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

Cancer. p53, guardian of the genome

Telomere length predicts replicative capacity of human fibroblasts

p53: puzzle and paradigm

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

Heterogeneity in Li-Fraumeni families: p53 mutation analysis and immunohistochemical staining

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance.

Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?

Li-Fraumeni syndrome--a molecular and clinical review.

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