Light chain of factor VIII is sufficient for accelerating cleavage of von Willebrand factor by ADAMTS13 metalloprotease.
about
Probing ADAMTS13 substrate specificity using phage displayStructure-function and regulation of ADAMTS-13 protease.Normal cleavage of von Willebrand factor by ADAMTS-13 in the absence of factor VIII in patients with severe hemophilia AMice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels.Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A mice.Compromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII.In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process.
P2860
Q35596768-C0CF2D7A-7FD2-4297-8F5D-8C93E6328FB7Q37019574-2756026F-6AD1-4A3A-B938-1B4B6DD1A0A5Q37171410-ED88021D-C41F-45A2-9AFF-291DABCFC6B3Q41512070-46ABDDD8-88AC-4696-BDA0-A099AB21EB7FQ45874015-88348064-EF78-4D84-8EBF-DDF971B6D3C5Q51026393-1ED8AC22-1FB0-4478-9633-77E6790E8F0CQ55241963-E45E6A74-2E0B-430C-9456-37228C8BA64E
P2860
Light chain of factor VIII is sufficient for accelerating cleavage of von Willebrand factor by ADAMTS13 metalloprotease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Light chain of factor VIII is ...... r by ADAMTS13 metalloprotease.
@ast
Light chain of factor VIII is ...... r by ADAMTS13 metalloprotease.
@en
type
label
Light chain of factor VIII is ...... r by ADAMTS13 metalloprotease.
@ast
Light chain of factor VIII is ...... r by ADAMTS13 metalloprotease.
@en
prefLabel
Light chain of factor VIII is ...... r by ADAMTS13 metalloprotease.
@ast
Light chain of factor VIII is ...... r by ADAMTS13 metalloprotease.
@en
P2093
P2860
P356
P1476
Light chain of factor VIII is ...... r by ADAMTS13 metalloprotease.
@en
P2093
Amy M Lange
Denise E Sabatino
Ekaterina Altynova
Rodney M Camire
Veronica C Casina
Wenjing Cao
X Long Zheng
P2860
P304
32459-32466
P356
10.1074/JBC.M112.390690
P407
P577
2012-08-01T00:00:00Z