Differential sialylation modulates voltage-gated Na+ channel gating throughout the developing myocardium
about
Regulated and aberrant glycosylation modulate cardiac electrical signaling.Cardiac Na Channels: Structure to FunctionSialic acids attached to N- and O-glycans within the Nav1.4 D1S5-S6 linker contribute to channel gating.Reduced sialylation impacts ventricular repolarization by modulating specific K+ channel isoforms distinctly.Decreased response to acetylcholine during aging of aplysia neuron R15.Functional features of trans-differentiated hair cells mediated by Atoh1 reveals a primordial mechanism.Physiologic and pathophysiologic consequences of altered sialylation and glycosylation on ion channel function.Mining the virgin land of neurotoxicology: a novel paradigm of neurotoxic peptides action on glycosylated voltage-gated sodium channels.The expression of hyperpolarization activated cyclic nucleotide gated (HCN) channels in the rat ovary are dependent on the type of cell and the reproductive age of the animal: a laboratory investigationThe role of Drosophila cytidine monophosphate-sialic acid synthetase in the nervous systemThe Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation.Tuning the electrical properties of the heart by differential trafficking of KATP ion channel complexes.Biology of cardiac sodium channel Nav1.5 expression.Modulation of voltage-gated ion channels by sialylation.Identifying potential functional impact of mutations and polymorphisms: linking heart failure, increased risk of arrhythmias and sudden cardiac deathThe role of protein N-glycosylation in neural transmissionN-glycan content modulates kainate receptor functional properties.Voltage-Gated Na+ Channels: Not Just for Conduction.Aberrant sialylation causes dilated cardiomyopathy and stress-induced heart failure.N-glycosylation in regulation of the nervous system.Sialyltransferase regulates nervous system function in Drosophila.Sialic acids attached to O-glycans modulate voltage-gated potassium channel gating.Defective polysialylation and sialylation induce opposite effects on gating of the skeletal Na+ channel NaV1.4 in Chinese hamster ovary cells.Pulsed magnetic stimulation modifies amplitude of action potentials in vitro via ionic channels-dependent mechanism.Structural heterogeneity promotes triggered activity, reflection and arrhythmogenesis in cardiomyocyte monolayers.Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.Endothelin-1 stimulates the expression of L-type Ca2+ channels in neonatal rat cardiomyocytes via the extracellular signal-regulated kinase 1/2 pathway.
P2860
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P2860
Differential sialylation modulates voltage-gated Na+ channel gating throughout the developing myocardium
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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name
Differential sialylation modul ...... hout the developing myocardium
@ast
Differential sialylation modul ...... hout the developing myocardium
@en
type
label
Differential sialylation modul ...... hout the developing myocardium
@ast
Differential sialylation modul ...... hout the developing myocardium
@en
prefLabel
Differential sialylation modul ...... hout the developing myocardium
@ast
Differential sialylation modul ...... hout the developing myocardium
@en
P2860
P356
P1476
Differential sialylation modul ...... hout the developing myocardium
@en
P2093
Eric S Bennett
Patrick J Stocker
P2860
P304
P356
10.1085/JGP.200509423
P577
2006-02-13T00:00:00Z