Cross talk between activation and slow inactivation gates of Shaker potassium channels
about
Structural basis for the coupling between activation and inactivation gates in K(+) channelsStructural mechanism of C-type inactivation in K(+) channelsVoltage gated ion channel function: gating, conduction, and the role of water and protonsCrystal structure of full-length KcsA in its closed conformationThe voltage-dependent gate in MthK potassium channels is located at the selectivity filterA molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channelA quantitative description of KcsA gating I: macroscopic currentsMolecular driving forces determining potassium channel slow inactivation.Mechanism of the modulation of Kv4:KChIP-1 channels by external K+Importance of lipid-pore loop interface for potassium channel structure and function.Modulation of Kir1.1 inactivation by extracellular Ca and Mg.Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.The pathway and spatial scale for MscS inactivation.Multiple modalities converge on a common gate to control K2P channel function.Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor.External K activation of Kir1.1 depends on the pH gateCalcium ions open a selectivity filter gate during activation of the MthK potassium channelPrinciples underlying energetic coupling along an allosteric communication trajectory of a voltage-activated K+ channel.Probing the cavity of the slow inactivated conformation of shaker potassium channels.Gating charge immobilization in Kv4.2 channels: the basis of closed-state inactivation.Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation.The neuronal Kv4 channel complex.Transfer of rolf S3-S4 linker to HERG eliminates activation gating but spares inactivation.Gating of two pore domain potassium channels.Being flexible: the voltage-controllable activation gate of kv channels.Much more than a leak: structure and function of K₂p-channels.Kir4.1 K+ channels are regulated by external cations.Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathwayExternal Ba2+ block of human Kv1.5 at neutral and acidic pH: evidence for Ho+-induced constriction of the outer pore mouth at rest.Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared SpectroscopyA direct demonstration of closed-state inactivation of K+ channels at low pH.Closed-state inactivation involving an internal gate in Kv4.1 channels modulates pore blockade by intracellular quaternary ammonium ions.Voltage-dependent biphasic effects of chloroquine on delayed rectifier K(+)-channel currents in murine thymocytes.Coupling of activation and inactivation gate in a K+-channel: potassium and ligand sensitivityAllosteric coupling of the inner activation gate to the outer pore of a potassium channel.Crystal structure of an inactivated mutant mammalian voltage-gated K+ channel.Interaction of the S6 proline hinge with N-type and C-type inactivation in Kv1.4 channels.External Ba(2+) block of Kv4.2 channels is enhanced in the closed-inactivated state.Mechanism of activation at the selectivity filter of the KcsA K+ channel.
P2860
Q24630519-6963D619-DCDA-4461-91DE-881794B72EC7Q24630547-20B4BF69-9E0C-416A-951E-05E06DD7C047Q26829808-2759794E-F6BE-4A41-9973-C8BF9569B2A2Q27654557-331240F1-D348-46D5-B9D5-20D2A7CB6F0EQ27675587-9237DCD1-4E8F-4BF8-9787-136D8636563DQ28579256-567EAF1C-3ECC-4ADD-9581-B92A62DDB764Q30442550-BDB6C361-B0D3-4E17-8042-A323B7621C43Q30444688-EB863F6F-EB81-4222-B47A-48A8490DF70AQ30481111-70D5BA31-30B2-43D0-B700-AC4BBDD52CB8Q34359619-91486C76-3665-43DD-AA77-EF700C9BE594Q34594757-5A792B6B-5ED6-4398-A236-2D6FB7CCBE56Q34800154-18D762DD-88E0-4FDB-B31F-3D87B5BD460EQ35102155-D24DDDF7-BB99-416A-9834-C2A3236DA014Q35236043-1F0355D2-D07A-4587-AC0A-499B352FEFC1Q35581364-0A967A54-9FDA-4C87-9CBC-E31D85F8BA18Q35787126-4D20D6CB-ECE9-4D08-A3BA-4F498F941BFAQ35850979-A63C3493-E5DF-4EEE-9BE9-7BAB8CF7B12CQ36087911-90AD6C7A-A726-4941-A9C3-E5D1DB2B8CE8Q36288877-81922977-F7E0-4C42-8166-C6C22F24A60FQ36299751-30681FF7-41F2-4933-A1EA-93977E3BF3A8Q36471344-4F43D10A-9C3E-4924-98CF-34CA457375F7Q36924275-8BCD19DB-5929-4C94-98B5-3F21C92D044DQ37115522-0DF6F011-9B82-421C-861A-DAB7CEAB1783Q37359431-C93E4D8E-E912-468A-B9E5-59F1BB98877FQ37766696-907E5202-5781-4F1F-BD2F-DFDDEB0BAA1EQ38044898-C2154252-1E41-44C6-8228-E3936C88EF4CQ38384425-9DD8F555-D872-42AD-995C-62E6D79C5C99Q39430985-8DA94A15-EB10-44C9-B9BA-8B97CC55650CQ39706375-343C8F66-22C5-4A90-AE71-913508B425E1Q39956876-2F8F6A0E-85BB-4266-8476-E2117164139EQ41262323-F29ED842-30C5-458B-B06D-0BE8CBA22575Q41828199-27D9927A-424A-4D00-B607-1A500E2B8D62Q41914490-A96CFC8C-B733-4B58-B9B1-751B0F5CD49FQ41930362-AE8EE8F0-6256-4C53-BFBA-429F98F65A21Q42028947-7EDD71E0-D6B7-4EA0-97FD-22DEEF52E380Q42035760-5208297C-9193-428B-801B-3217C988DFEBQ42381160-6B83FB93-42A6-442B-B759-22075367150DQ42425934-DD587617-1013-40F6-9ED5-B37F841C01E4Q43504598-AE02A58B-A6BE-469D-951B-5C0BB6E9BA94Q44232952-38C2AA08-5695-4ABC-8FB0-38FCB7A48604
P2860
Cross talk between activation and slow inactivation gates of Shaker potassium channels
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Cross talk between activation and slow inactivation gates of Shaker potassium channels
@ast
Cross talk between activation and slow inactivation gates of Shaker potassium channels
@en
type
label
Cross talk between activation and slow inactivation gates of Shaker potassium channels
@ast
Cross talk between activation and slow inactivation gates of Shaker potassium channels
@en
prefLabel
Cross talk between activation and slow inactivation gates of Shaker potassium channels
@ast
Cross talk between activation and slow inactivation gates of Shaker potassium channels
@en
P2860
P356
P1476
Cross talk between activation and slow inactivation gates of Shaker potassium channels
@en
P2093
Carol Deutsch
Gyorgy Panyi
P2860
P304
P356
10.1085/JGP.200609644
P577
2006-10-16T00:00:00Z