Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.
about
TRPV1: a target for next generation analgesicsTRPV1: on the road to pain reliefGPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M currentTRPV1: A Target for Rational Drug DesignAnti-nerve growth factor in pain management: current evidenceEmerging Role of Spinal Cord TRPV1 in Pain ExacerbationIntegrating TRPV1 Receptor Function with Capsaicin PsychophysicsRegulation of transient receptor potential channels by the phospholipase C pathwayFunctionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel--an overview of the current mutational dataNerve growth factor-mediated regulation of pain signalling and proposed new intervention strategies in clinical pain managementTRP channels and analgesiaLipid kinases as therapeutic targets for chronic painNear-membrane dynamics and capture of TRPM8 channels within transient confinement domainsVAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8.TNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18-1/syntaxin1/SNAP-25 mediated fusion.Distinct properties of Ca 2+ –calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channelAtypical sensors for direct and rapid neuronal detection of bacterial pathogensNerve growth factor and diarrhea-predominant irritable bowel syndrome (IBS-D): a potential therapeutic target?Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neuronsDifferential regulation of proton-sensitive ion channels by phospholipids: a comparative study between ASICs and TRPV1A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlicUrothelial signaling.Determinants of molecular specificity in phosphoinositide regulation. Phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) is the endogenous lipid regulating TRPV1.Dynamic visualization of membrane-inserted fraction of pHluorin-tagged channels using repetitive acidification technique.Interaction with phosphoinositides confers adaptation onto the TRPV1 pain receptor.Regulation of TRPV1 ion channel by phosphoinositide (4,5)-bisphosphate: the role of membrane asymmetryRegulation of the putative TRPV1t salt taste receptor by phosphatidylinositol 4,5-bisphosphateDifferential distribution of PI3K isoforms in spinal cord and dorsal root ganglia: potential roles in acute inflammatory painType III Nrg1 back signaling enhances functional TRPV1 along sensory axons contributing to basal and inflammatory thermal pain sensationDifferential modulation of agonist and antagonist structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitorsStructural determinants of the transient receptor potential 1 (TRPV1) channel activation by phospholipid analogsNerve growth factor sensitizes adult sympathetic neurons to the proinflammatory peptide bradykinin.Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate.Integrative binding sites within intracellular termini of TRPV1 receptor.Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.Voltage- and temperature-dependent activation of TRPV3 channels is potentiated by receptor-mediated PI(4,5)P2 hydrolysis.Neurotrophin signaling and visceral hypersensitivityDissection of the components for PIP2 activation and thermosensation in TRP channelsLocalization of the PIP2 sensor of TRPV1 ion channels
P2860
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P2860
Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane.
description
2006 nî lūn-bûn
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2006年の論文
@ja
2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
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2006年學術文章
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name
Phosphoinositide 3-kinase bind ...... icking to the plasma membrane.
@ast
Phosphoinositide 3-kinase bind ...... icking to the plasma membrane.
@en
type
label
Phosphoinositide 3-kinase bind ...... icking to the plasma membrane.
@ast
Phosphoinositide 3-kinase bind ...... icking to the plasma membrane.
@en
prefLabel
Phosphoinositide 3-kinase bind ...... icking to the plasma membrane.
@ast
Phosphoinositide 3-kinase bind ...... icking to the plasma membrane.
@en
P2093
P2860
P356
P1476
Phosphoinositide 3-kinase bind ...... ficking to the plasma membrane
@en
P2093
Alexander T Stein
Carmen A Ufret-Vincenty
Sharona E Gordon
P2860
P304
P356
10.1085/JGP.200609576
P577
2006-11-01T00:00:00Z