Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.
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Tracheal development and the von Hippel-Lindau tumor suppressor homolog in DrosophilaRegulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alphaChordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesisCCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signalingExpression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breastVanadate-induced expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen speciesExpression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stressInhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growthHypoxia and oxidative stress in breast cancer. Hypoxia signalling pathwaysHypoxia and oxidative stress in breast cancer. Hypoxia and tumourigenesisBreast cancer-induced angiogenesis: multiple mechanisms and the role of the microenvironmentLactate Dehydrogenase in Hepatocellular Carcinoma: Something Old, Something NewHypoxic control of metastasisPharmacologic resistance in colorectal cancer: a reviewThe three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implicationsHypoxia and Integrin-Mediated Epithelial Restitution during Mucosal InflammationHepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1 and Stimulates the Synthesis of Vascular Endothelial Growth FactorVHL mutations and their correlation with tumour cell proliferation, microvessel density, and patient prognosis in clear cell renal cell carcinoma.The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated MacrophagesHypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effectInteraction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxiaRelation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survivalHypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survivalMutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathwayA novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cellsChick embryo partial ischemia model: a new approach to study ischemia ex vivoA sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatusPortosystemic shunting and persistent fetal vascular structures in aryl hydrocarbon receptor-deficient miceInactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein.Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeuticsThe impact of O2 availability on human cancerRegulation of hypoxia adaptation: an overlooked virulence attribute of pathogenic fungi?A conserved helical capping hydrogen bond in PAS domains controls signaling kinetics in the superfamily prototype photoactive yellow protein.Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration.Molecular mechanism of hypoxia-inducible factor 1alpha -p300 interaction. A leucine-rich interface regulated by a single cysteine.Tumoral environment triggers transcript anomalies in established tumors: induction of altered gene expression and of aberrant, truncated and B2 repeat-containing gene transcriptsNatural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1).A novel role for 3, 4-dichloropropionanilide (DCPA) in the inhibition of prostate cancer cell migration, proliferation, and hypoxia-inducible factor 1alpha expression.Xenopus Dab2 is required for embryonic angiogenesis
P2860
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P2860
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.
@ast
Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.
@en
type
label
Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.
@ast
Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.
@en
prefLabel
Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.
@ast
Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth.
@en
P2093
P2860
P50
P356
P1476
Hypoxia-inducible factor-1 mod ...... angiogenesis and tumor growth
@en
P2093
L G Nicholls
O Hankinson
P H Maxwell
P2860
P304
P356
10.1073/PNAS.94.15.8104
P407
P577
1997-07-01T00:00:00Z