Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.

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Recent advances in targeting mTOR signaling pathway using small molecule inhibitors.Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease

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Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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name

Suppression of the GTPase-acti ...... aling in ovarian cancer cells.

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Suppression of the GTPase-acti ...... aling in ovarian cancer cells.

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Suppression of the GTPase-acti ...... aling in ovarian cancer cells.

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Suppression of the GTPase-acti ...... aling in ovarian cancer cells.

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prefLabel

Suppression of the GTPase-acti ...... aling in ovarian cancer cells.

@ast

Suppression of the GTPase-acti ...... aling in ovarian cancer cells.

@en

P1476

Suppression of the GTPase-acti ...... aling in ovarian cancer cells.

@en

P2093

Ali A Alshamrani

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Ha T Nguyen

http://www.w3.org/2001/XMLSchema#string

Jada M Fambrough

http://www.w3.org/2001/XMLSchema#string

Mandi M Murph

http://www.w3.org/2001/XMLSchema#string

Mihir B Patel

http://www.w3.org/2001/XMLSchema#string

Molly K Altman

http://www.w3.org/2001/XMLSchema#string

Pooya Hoseinzadeh

http://www.w3.org/2001/XMLSchema#string

Wei Jia

http://www.w3.org/2001/XMLSchema#string

P2860

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

Rheb binds and regulates the mTOR kinase

RGS10 is a selective activator of G alpha i GTPase activity

A high throughput screen for RGS proteins using steady state monitoring of free phosphate formation

Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1.

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175-183

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scholarly article

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10.1016/J.CANLET.2015.08.012

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English

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369

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Aaron M. Beedle

Sterling Tran

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2015-08-28T00:00:00Z

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26319900

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P921

ovarian cancer

P932

4654121

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Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.

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P2860

P2860

Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932