Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention.
about
Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomesIntegrating cellular metabolism into a multiscale whole-body modelMice deficient in Cu,Zn-superoxide dismutase are resistant to acetaminophen toxicityDifferential Cytotoxicity of Acetaminophen in Mouse Macrophage J774.2 and Human Hepatoma HepG2 Cells: Protection by Diallyl SulfideSelective protein arylation and acetaminophen-induced hepatotoxicity.Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches.Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry.Update: the clinical importance of acetaminophen hepatotoxicity in non-alcoholic and alcoholic subjects.Acetaminophen-NAPQI hepatotoxicity: a cell line model system genome-wide association study.Biomonitoring of arylamines and nitroarenes.Pharmacological screening of glycine amino acid prodrug of acetaminophen.Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.Formononetin protects against acetaminophen-induced hepatotoxicity through enhanced NRF2 activity.Pharmacogenetic selection of transplanted human hepatocytes in immunocompetent rats.Hepatoprotective effect of ethanolic extract of Trichosanthes lobata on paracetamol-induced liver toxicity in rats.Overexpression of Aldose Reductase Render Mouse Hepatocytes More Sensitive to Acetaminophen Induced Oxidative Stress and Cell Death.Role of the Nrf2-ARE pathway in liver diseasesComparative Hepatoprotective Activity of Ethanolic Extracts of Cuscuta australis against Acetaminophen Intoxication in Wistar Rats.Hepatoprotective and Antioxidant Activity of Dunaliella salina in Paracetamol-induced Acute Toxicity in Rats.Antioxidants of Phyllanthus emblica L. Bark Extract Provide Hepatoprotection against Ethanol-Induced Hepatic Damage: A Comparison with SilymarinTaurine and liver diseases: a focus on the heterogeneous protective properties of taurine.Animal models of hepatotoxicity.Potential preventive role of Iranian Achillea wilhelmsii C. Koch essential oils in acetaminophen-induced hepatotoxicityMechanisms of the formation and disposition of reactive metabolites that can cause acute liver injury.Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury.Cytotoxicity and cytoprotective activities of natural compounds. The case of curcumin.Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: role of drug metabolizing microsomal enzyme system, tumor necrosis factor-alpha and fate of liver cell structural integrity.Effect of antimalarials treatment on rat liver lysosomal function-Anin vivo study.Comparison of thermally oxidized lipids and acetaminophen with concurrent consumption of ethanol as inducers of liver cirrhosis.Lipid-lowering and hepatoprotective effects of Vitis vinifera dried seeds on paracetamol-induced hepatotoxicity in rats.Is activation of lysosomal enzymes responsible for paracetamol-induced hepatotoxicity and nephrotoxicity?Carotenoid lutein protects rats from paracetamol-, carbon tetrachloride- and ethanol-induced hepatic damage.Evaluation of nephroprotective, diuretic, and antioxidant activities of plectranthus amboinicus on acetaminophen-induced nephrotoxic rats.Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1.Comparative impacts of knockouts of two antioxidant enzymes on acetaminophen-induced hepatotoxicity in mice.Role of taurine in preventing acetaminophen-induced hepatic injury in the rat.Tyrosinase-mediated oxidation of acetaminophen to 4-acetamido-o-benzoquinone.Antioxidant and hepatoprotective effects of Capparis spinosa L. fractions and Quercetin on tert-butyl hydroperoxide- induced acute liver damage in mice.Acetaminophen toxicity. Opposite effects of two forms of glutathione peroxidase.Abrogation by Trifolium alexandrinum root extract on hepatotoxicity induced by acetaminophen in rats.
P2860
Q24311331-872EEECA-01D0-41C6-B45F-B045D240D60FQ28484829-34A3BAEC-4D58-4DC0-A1B5-D0242CB25592Q28507722-DFB3B275-034F-4F6A-8AC1-D4D393283E22Q28551818-75833C03-E369-4566-8F56-76AA1F23ADEDQ30427535-EEABD718-CFDA-492F-9A71-88142182B969Q32052639-90F22ECC-E2D7-487B-B217-E668B08B44ACQ32058433-19263534-FC8B-475D-A534-59FFB554AA66Q34109283-09E6F66E-2C0B-4DD4-9737-25154A88E992Q34601408-D0AA2E58-2989-4619-81EC-05E95F6DD0A8Q35001236-3CE71646-7EB1-434C-9376-854ACC85F8F2Q35276961-CE0576CB-0B8C-4AB7-B531-365DD8241D2CQ35823922-90E99E0B-959C-4806-AD12-E4B38572CE2DQ36289550-4537247F-3198-46C0-BDE8-3CB27F676BE3Q36364143-1A0984EC-1AC1-4FDB-9B95-67EA2A2A584CQ36368103-ABECF80E-3D52-4CDD-B406-D08C2661D52FQ36764157-F95A0A14-FBD1-4797-9280-390CD96BBEEDQ36879950-1C203AD4-3CA9-460D-9DFD-6CAD4F0E6714Q36978954-1AA4CB31-6B95-4F2D-A712-DA3BF74562DBQ37592419-E1FE6BB5-07B2-4F84-9752-E1E75FBB922CQ37607545-8FB07946-023E-4FDB-A81E-EA0DF701C313Q38037378-D9DF5682-AD5F-48A1-BEAA-0CE10A64AAB4Q38596917-7477A67F-D873-4359-B6F8-C2CFA590AD31Q38782581-9974E5F7-8133-47A1-A128-693D3A5E0174Q40463530-D0AF7B64-18F2-40DF-8F34-131A1DEAA4C7Q40817414-ACA914C8-6957-4DA0-8646-B5841322AAEEQ41119927-6B90E8D2-BB53-449B-89C8-9C2A4C079433Q41877696-3F08523A-95AB-408F-9EEE-0B3144CF3AACQ41912963-3844B88B-4FA7-49CB-9B7C-CB908AC777CCQ42276190-7B8F0A9B-3992-48F0-8219-F41F7D65F8FEQ42553678-D2EFAAB8-36A0-42F3-A03A-D1E91C32B15FQ42554207-7A77A459-DF91-4F64-A8DC-AD4EF6007AA0Q42956082-38579BEC-EAFE-4B79-BAED-B0D05238EB71Q43109563-26797CB3-31DD-47BA-958A-E34C8A7AEE85Q43157749-249E0400-1586-4790-B2AD-E73CE9920360Q43236631-7AF43E47-B4C8-4999-BBD7-A8DF3E49B370Q43607613-6E9855B8-A1C0-4234-80D0-9C6ACC7E5014Q44293873-D5CE47D5-F453-4A5A-B065-77CA3F888C26Q49341206-EE8226F1-CB38-41CE-9F15-2288AA5CB552Q54100952-E0D87FB1-63FE-473D-99B1-317550E607B9Q54659950-F31FD7A6-4568-4CA7-8F2B-A9304A6A34A5
P2860
Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Molecular aspects of paracetam ...... ts mechanism-based prevention.
@ast
Molecular aspects of paracetam ...... ts mechanism-based prevention.
@en
type
label
Molecular aspects of paracetam ...... ts mechanism-based prevention.
@ast
Molecular aspects of paracetam ...... ts mechanism-based prevention.
@en
prefLabel
Molecular aspects of paracetam ...... ts mechanism-based prevention.
@ast
Molecular aspects of paracetam ...... ts mechanism-based prevention.
@en
P2093
P2860
P1476
Molecular aspects of paracetam ...... ts mechanism-based prevention.
@en
P2093
J G Bessems
N P Vermeulen
R Van de Straat
P2860
P304
P356
10.3109/03602539208996298
P407
P577
1992-01-01T00:00:00Z