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HIV-infected T cells are migratory vehicles for viral dissemination

HIV-infected T cells are migratory vehicles for viral dissemination

http://www.wikidata.org/entity/Q36315429

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Hybrid spreading mechanisms and T cell activation shape the dynamics of HIV-1 infection HIV-1 induced bystander apoptosis High multiplicity HIV-1 cell-to-cell transmission from macrophages to CD4+ T cells limits antiretroviral efficacy In vivo imaging of virological synapses.Advancing biomedical imaging HIV-1 Infection of T Lymphocytes and Macrophages Affects Their Migration via Nef The immunological synapse: the gateway to the HIV reservoir New generation humanized mice for virus research: comparative aspects and future prospects Normal and tumoral melanocytes exhibit q-Gaussian random search patterns High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral function Comparative Analysis of Immune Activation Markers of CD8(+) T Cells in Lymph Nodes of Different Origins in SIV-Infected Chinese Rhesus Macaques Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish Characterizing natural hydrogel for reconstruction of three-dimensional lymphoid stromal network to model T-cell interactions.Immune restoration after antiretroviral therapy: the pitfalls of hasty or incomplete repairs.Where in the Cell Are You? Probing HIV-1 Host Interactions through Advanced Imaging Techniques Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice HIV Replication Is Not Controlled by CD8+ T Cells during the Acute Phase of the Infection in Humanized Mice In vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis.Long-distance relationships: do membrane nanotubes regulate cell-cell communication and disease progression?HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo.Orai1 function is essential for T cell homing to lymph nodes Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.Three-dimensional imaging of HIV-1 virological synapses reveals membrane architectures involved in virus transmission.Contact-induced mitochondrial polarization supports HIV-1 virological synapse formation.HIV-1 Gag, Envelope, and Extracellular Determinants Cooperate To Regulate the Stability and Turnover of Virological Synapses.Imaging the beating heart in the mouse using intravital microscopy techniques.Biosafety Level 3 setup for multiphoton microscopy in vivo.Similarity in viral and host promoters couples viral reactivation with host cell migration Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.Human T-Cell Development and Thymic Egress: An Infectious Disease Perspective Association between latent proviral characteristics and immune activation in antiretrovirus-treated human immunodeficiency virus type 1-infected adults Fitness impaired drug resistant HIV-1 is not compromised in cell-to-cell transmission or establishment of and reactivation from latency Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.Partial rescue of V1V2 mutant infectivity by HIV-1 cell-cell transmission supports the domain's exceptional capacity for sequence variation.Preclinical evaluation of the immunomodulatory lymphocyte trafficking drug FTY720 for HIV prevention in the female genital mucosa of macaques Automated image-based assay for evaluation of HIV neutralization and cell-to-cell fusion inhibition.Thirty years on: HIV receptor gymnastics and the prevention of infection Macrophage infection via selective capture of HIV-1-infected CD4+ T cells.

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HIV-infected T cells are migratory vehicles for viral dissemination

http://www.wikidata.org/entity/Q36315429

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2012年學術文章

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2012年學術文章

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HIV-infected T cells are migratory vehicles for viral dissemination

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HIV-infected T cells are migratory vehicles for viral dissemination

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Andrew D Luster

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Andrew M Tager

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Edward Seung

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Francesco Marangoni

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Maud Deruaz

http://www.w3.org/2001/XMLSchema#string

Thomas T Murooka

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Thorsten R Mempel

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Vladimir D Vrbanac

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P2860

Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse

Avoiding the void: cell-to-cell spread of human viruses

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

Nucleocapsid promotes localization of HIV-1 gag to uropods that participate in virological synapses between T cells

Tetherin restricts productive HIV-1 cell-to-cell transmission

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes

Early events in sexual transmission of HIV and SIV and opportunities for interventions.

Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses.

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283-287

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10.1038/NATURE11398

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7419

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490

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Ulrich von Andrian

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2012-08-01T00:00:00Z

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230599110

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1044805538

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22854780

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3470742

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