Heterophilic binding of L1 on unmyelinated sensory axons mediates Schwann cell adhesion and is required for axonal survival.
about
RanBPM is an L1-interacting protein that regulates L1-mediated mitogen-activated protein kinase activationRole of Schwann cells in the regeneration of penile and peripheral nervesNeuregulin-1 type III determines the ensheathment fate of axonsThe neural recognition molecule L1 is a sialic acid-binding lectin for CD24, which induces promotion and inhibition of neurite outgrowthAlteration of the cell adhesion molecule L1 expression in a specific subset of primary afferent neurons contributes to neuropathic painMesenchymal stem cells facilitate axon sorting, myelination, and functional recovery in paralyzed mice deficient in Schwann cell-derived laminin.Identification of novel cell-adhesion molecules in peripheral nerves using a signal-sequence trapExpression of ATF3 and axonal outgrowth are impaired after delayed nerve repair.An integrin-contactin complex regulates CNS myelination by differential Fyn phosphorylation.Mouse olfactory ensheathing glia enhance axon outgrowth on a myelin substrate in vitroA central role for Necl4 (SynCAM4) in Schwann cell-axon interaction and myelination.Role for the epidermal growth factor receptor in neurofibromatosis-related peripheral nerve tumorigenesis.L1-mediated branching is regulated by two ezrin-radixin-moesin (ERM)-binding sites, the RSLE region and a novel juxtamembrane ERM-binding region.Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo.Genetic and clinical aspects of X-linked hydrocephalus (L1 disease): Mutations in the L1CAM gene.Promotion of spinal cord regeneration by neural stem cell-secreted trimerized cell adhesion molecule L1.Axonal and Schwann cell BACE1 is equally required for remyelination of peripheral nerves.Role of the cytoplasmic domain of the L1 cell adhesion molecule in brain development.Function-triggering antibodies to the adhesion molecule L1 enhance recovery after injury of the adult mouse femoral nerve.Evolution of a neuroprotective function of central nervous system myelin.Plasmin-sensitive dibasic sequences in the third fibronectin-like domain of L1-cell adhesion molecule (CAM) facilitate homomultimerization and concomitant integrin recruitmentCD44 enhances neuregulin signaling by Schwann cells.Disrupted Schwann cell-axon interactions in peripheral nerves of mice with altered L1-integrin interactionsErbin is required for myelination in regenerated axons after injury.Genetic deletion of BACE1 in mice affects remyelination of sciatic nervesExpression changes of nerve cell adhesion molecules L1 and semaphorin 3A after peripheral nerve injury.Ankyrin protein networks in membrane formation and stabilization.Concepts for regulation of axon integrity by enwrapping glia.Does the preclinical evidence for functional remyelination following myelinating cell engraftment into the injured spinal cord support progression to clinical trials?Human L1CAM carrying the missense mutations of the fibronectin-like type III domains is localized in the endoplasmic reticulum and degraded by polyubiquitylation.Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.L1 mediated homophilic binding and neurite outgrowth are modulated by alternative splicing of exon 2.The third fibronectin type III repeat is required for L1 to serve as an optimal substratum for neurite extension.L1 cell adhesion molecule is essential for the maintenance of hyperalgesia after spinal cord injury.Disruption of laminin in the peripheral nervous system impedes nonmyelinating Schwann cell development and impairs nociceptive sensory function.Disruption of fibroblast growth factor receptor signaling in nonmyelinating Schwann cells causes sensory axonal neuropathy and impairment of thermal pain sensitivity.Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells.Gold nanoparticles functionalized with a fragment of the neural cell adhesion molecule L1 stimulate L1-mediated functions.Graded Elevation of c-Jun in Schwann Cells In Vivo: Gene Dosage Determines Effects on Development, Remyelination, Tumorigenesis, and Hypomyelination.A co-culture microtunnel technique demonstrating a significant contribution of unmyelinated Schwann cells to the acceleration of axonal conduction in Schwann cell-regulated peripheral nerve development.
P2860
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P2860
Heterophilic binding of L1 on unmyelinated sensory axons mediates Schwann cell adhesion and is required for axonal survival.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Heterophilic binding of L1 on ...... required for axonal survival.
@ast
Heterophilic binding of L1 on ...... required for axonal survival.
@en
type
label
Heterophilic binding of L1 on ...... required for axonal survival.
@ast
Heterophilic binding of L1 on ...... required for axonal survival.
@en
prefLabel
Heterophilic binding of L1 on ...... required for axonal survival.
@ast
Heterophilic binding of L1 on ...... required for axonal survival.
@en
P2093
P2860
P356
P1476
Heterophilic binding of L1 on ...... s required for axonal survival
@en
P2093
P2860
P304
P356
10.1083/JCB.146.5.1173
P407
P577
1999-09-01T00:00:00Z