Granuphilin molecularly docks insulin granules to the fusion machinery. - Wikidata - wikimedia - TriplyDB

Granuphilin molecularly docks insulin granules to the fusion machinery.

Granuphilin molecularly docks insulin granules to the fusion machinery.

http://www.wikidata.org/entity/Q36320435

about

Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain β-Cell MicroRNAs: Small but Powerful Multiple roles for the actin cytoskeleton during regulated exocytosis MicroRNAs in insulin resistance and obesity Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis Resident CAPS on dense-core vesicles docks and primes vesicles for fusion A novel role for the centrosomal protein, pericentrin, in regulation of insulin secretory vesicle docking in mouse pancreatic beta-cells Granuphilin exclusively mediates functional granule docking to the plasma membrane.MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells Neurexin-1α contributes to insulin-containing secretory granule docking Distinct actions of Rab3 and Rab27 GTPases on late stages of exocytosis of insulin.Regulation of cellular communication by signaling microdomains in the blood vessel wall.Exophilin8 transiently clusters insulin granules at the actin-rich cell cortex prior to exocytosis.The interplay between the Rab27A effectors Slp4-a and MyRIP controls hormone-evoked Weibel-Palade body exocytosis.The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane.Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells.Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa.Mapping dynamic protein interactions to insulin secretory granule behavior with TIRF-FRET.Gene networks modified by sulphonylureas in beta cells: a pathway-based analysis of insulin secretion and cell death.ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis.Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice.Minireview: microRNA function in pancreatic β cells.Altered pancreatic islet function and morphology in mice lacking the Beta-cell surface protein neuroligin-2.Expression of Secretogranin III in Chicken Endocrine Cells: Its Relevance to the Secretory Granule Properties of Peptide Prohormone Processing and Bioactive Amine Content.Survey of Red Fluorescence Proteins as Markers for Secretory Granule Exocytosis Modular genetic control of sexually dimorphic behaviors.Evolving insights regarding mechanisms for the inhibition of insulin release by norepinephrine and heterotrimeric G proteins.In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice On the immense variety and complexity of circumstances conditioning pancreatic β-cell apoptosis in type 1 diabetes Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane.PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport.Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells Insulin vesicle release: walk, kiss, pause ... then run.Role of Rab27 in synaptic transmission at the squid giant synapse Secretory vesicle docking to the plasma membrane: molecular mechanism and functional significance.

P2860

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P2860

Granuphilin molecularly docks insulin granules to the fusion machinery.

http://www.wikidata.org/entity/Q36320435

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh

2005年學術文章

@zh-hant

name

Granuphilin molecularly docks insulin granules to the fusion machinery.

@ast

Granuphilin molecularly docks insulin granules to the fusion machinery.

@en

type

label

Granuphilin molecularly docks insulin granules to the fusion machinery.

@ast

Granuphilin molecularly docks insulin granules to the fusion machinery.

@en

prefLabel

Granuphilin molecularly docks insulin granules to the fusion machinery.

@ast

Granuphilin molecularly docks insulin granules to the fusion machinery.

@en

P1433

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P1476

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P2093

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P2860

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P31

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P407

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P433

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P478

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Q36320435-4EB7865B-DE84-4504-B670-D3F2E44E975C

P577

Q36320435-AFDF7CE4-D09F-44C9-B5CE-BB48ADDE51BD

P5875

Q36320435-308031F5-0046-41A3-BF5E-2BF0585F6675

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P932

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P356

P1433

Journal of Cell Biology

P1476

Granuphilin molecularly docks insulin granules to the fusion machinery

@en

P2093

Hiroshi Gomi

http://www.w3.org/2001/XMLSchema#string

Kazuo Kasai

http://www.w3.org/2001/XMLSchema#string

Shin Mizutani

http://www.w3.org/2001/XMLSchema#string

Tetsuro Izumi

http://www.w3.org/2001/XMLSchema#string

P2860

A conformational switch in syntaxin during exocytosis: role of munc18.

Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a

The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules

Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice

Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex

Snares and Munc18 in synaptic vesicle fusion

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells

Munc18-1 promotes large dense-core vesicle docking

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

P304

99-109

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P31

scholarly article

P356

10.1083/JCB.200505179

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P407

P433

1

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P478

171

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P50

P577

2005-10-01T00:00:00Z

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P5875

7548984

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P698

16216924

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P921

P932

2171228

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