PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitter
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Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegansMolecular regulation of NKCC2 in the thick ascending limbDistinct initial SNARE configurations underlying the diversity of exocytosisPKA controls calcium influx into motor neurons during a rhythmic behaviorPositional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretionStructural and functional analysis of tomosyn identifies domains important in exocytotic regulationcAMP stimulates apical exocytosis of the renal Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in the thick ascending limb: role of protein kinase AA fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2.Tomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats.Reprogramming of G protein-coupled receptor recycling and signaling by a kinase switch.Tomosyn negatively regulates CAPS-dependent peptide release at Caenorhabditis elegans synapsesSyntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.Tomosyn interacts with the SUMO E3 ligase PIASγ.Modulating vesicle priming reveals that vesicle immobilization is necessary but not sufficient for fusion-competence.A presynaptic role for PKA in synaptic tagging and memory.Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion.Vesicle-associated membrane protein 2 (VAMP2) but Not VAMP3 mediates cAMP-stimulated trafficking of the renal Na+-K+-2Cl- co-transporter NKCC2 in thick ascending limbsPlatelet secretion and hemostasis require syntaxin-binding protein STXBP5.Tomosyn expression pattern in the mouse hippocampus suggests both presynaptic and postsynaptic functions.Vesicle-associated membrane protein-2 (VAMP2) mediates cAMP-stimulated renin release in mouse juxtaglomerular cells.Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memoryA Combined Optogenetic-Knockdown Strategy Reveals a Major Role of Tomosyn in Mossy Fiber Synaptic Plasticity.β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretionNeuron-specific expression of tomosyn1 in the mouse hippocampal dentate gyrus impairs spatial learning and memory.Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release.A longitudinal study of Caenorhabditis elegans larvae reveals a novel locomotion switch, regulated by G(αs) signalingReciprocal intramolecular interactions of tomosyn control its inhibitory activity on SNARE complex formation.Opposing actions of environmental enrichment and Alzheimer's disease on the expression of hippocampal microRNAs in mouse modelsFriends and foes in synaptic transmission: the role of tomosyn in vesicle priming.Kinetic barriers to SNAREpin assembly in the regulation of membrane docking/priming and fusion.KIF5B motor adaptor syntabulin maintains synaptic transmission in sympathetic neurons.Rescuing the subprime meltdown in insulin exocytosis in diabetes.Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn.Receptor-mediated regulation of tomosyn-syntaxin 1A interactions in bovine adrenal chromaffin cells.Ca/Calmodulin and presynaptic short-term plasticity.Tomosyn associates with secretory vesicles in neurons through its N- and C-terminal domains.The ubiquitin-proteasome system functionally links neuronal Tomosyn-1 to dendritic morphology.Millisecond Ca2+ dynamics activate multiple protein cascades for synaptic vesicle control.Protein phosphatase-1M and Rho-kinase affect exocytosis from cortical synaptosomes and influence neurotransmission at a glutamatergic giant synapse of the rat auditory system.Frontline Science: Tumor necrosis factor-α stimulation and priming of human neutrophil granule exocytosis.
P2860
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P2860
PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitter
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
PKA-catalyzed phosphorylation ...... exocytosis of neurotransmitter
@ast
PKA-catalyzed phosphorylation ...... exocytosis of neurotransmitter
@en
type
label
PKA-catalyzed phosphorylation ...... exocytosis of neurotransmitter
@ast
PKA-catalyzed phosphorylation ...... exocytosis of neurotransmitter
@en
prefLabel
PKA-catalyzed phosphorylation ...... exocytosis of neurotransmitter
@ast
PKA-catalyzed phosphorylation ...... exocytosis of neurotransmitter
@en
P2093
P2860
P921
P356
P1476
PKA-catalyzed phosphorylation ...... exocytosis of neurotransmitter
@en
P2093
Sumiko Mochida
Takeshi Baba
Toshiaki Sakisaka
Yoshimi Takai
P2860
P304
P356
10.1083/JCB.200504055
P407
P577
2005-09-01T00:00:00Z