A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis.
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Extracellular alkaline pH leads to increased metastatic potential of estrogen receptor silenced endocrine resistant breast cancer cellsPositive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cellsExpression of actin-interacting protein 1 suppresses impaired chemotaxis of Dictyostelium cells lacking the Na+-H+ exchanger NHE1Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide bindingAsymmetric localization of calpain 2 during neutrophil chemotaxis.Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling.The IplA Ca2+ channel of Dictyostelium discoideum is necessary for chemotaxis mediated through Ca2+, but not through cAMP, and has a fundamental role in natural aggregation.The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunitPDGFRα signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90RSK and AKT signaling pathwaysNa⁺/H⁺ exchangers and intracellular pH in perinatal brain injury.Involvement of signaling molecules on na/h exchanger-1 activity in human monocytes.The cofilin pathway in breast cancer invasion and metastasisNhe1 is essential for potassium but not calcium facilitation of cell motility and the monovalent cation requirement for chemotactic orientation in Dictyostelium discoideumThe sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factorsIncreased H⁺ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression.Intracellular pH sensors: design principles and functional significance.Chaperone activation by unfolding.Emerging roles of alkali cation/proton exchangers in organellar homeostasis.The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium.Plant NHX cation/proton antiportersRoles of ion transport in control of cell motility.pH dependence of melanoma cell migration: protons extruded by NHE1 dominate protons of the bulk solution.Tyrosine phosphorylation-mediated signaling pathways in dictyosteliumNa(+) /H(+) exchanger 1 (NHE1) function is necessary for maintaining mammary tissue architecture.The physiological regulation of macropinocytosis during Dictyostelium growth and development.Pollen tubes lacking a pair of K+ transporters fail to target ovules in Arabidopsis.Characterization of PEBBLEs as a Tool for Real-Time Measurement ofDictyostelium discoideumEndosomal pH
P2860
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P2860
A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
A developmentally regulated Na ...... ll polarity during chemotaxis.
@ast
A developmentally regulated Na ...... ll polarity during chemotaxis.
@en
type
label
A developmentally regulated Na ...... ll polarity during chemotaxis.
@ast
A developmentally regulated Na ...... ll polarity during chemotaxis.
@en
prefLabel
A developmentally regulated Na ...... ll polarity during chemotaxis.
@ast
A developmentally regulated Na ...... ll polarity during chemotaxis.
@en
P2860
P356
P1476
A developmentally regulated Na ...... ll polarity during chemotaxis.
@en
P2093
Diane L Barber
Hitesh Patel
P2860
P304
P356
10.1083/JCB.200412145
P407
P577
2005-04-01T00:00:00Z