Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity. - Wikidata - wikimedia - TriplyDB

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

http://www.wikidata.org/entity/Q36321606

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Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling FoxO3a is activated and executes neuron death via Bim in response to β-amyloid The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells Ribosylation rapidly induces alpha-synuclein to form highly cytotoxic molten globules of advanced glycation end products.FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice Oxidative stress: Biomarkers and novel therapeutic pathways.New strategies for Alzheimer's disease and cognitive impairment.p53 and mitochondrial function in neurons.The "O" class: crafting clinical care with FoxO transcription factors.Cyclopentenone isoprostanes are novel bioactive products of lipid oxidation which enhance neurodegeneration p66Shc--a longevity redox protein in human prostate cancer progression and metastasis : p66Shc in cancer progression and metastasis.SIRT1 regulates dendritic development in hippocampal neurons.Prooxidant properties of p66shc are mediated by mitochondria in human cells Unraveling the role of FoxOs in bone--insights from mouse models.Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis.Neuroprotective Activity of Sibjeondaebo-tang on Aβ Peptide-Induced Damages Arsenic trioxide-induced growth arrest of breast cancer MCF-7 cells involving FOXO3a and IκB kinase β expression and localization.In control of biology: of mice, men and Foxes Regulatory effects of the mitochondrial energetic status on mitochondrial p66Shc.OutFOXOing disease and disability: the therapeutic potential of targeting FoxO proteins Electrophilic cyclopentenone isoprostanes in neurodegeneration.Clever cancer strategies with FoxO transcription factors.p66Shc, oxidative stress and aging: importing a lifespan determinant into mitochondria p66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 mem A "FOXO" in sight: targeting Foxo proteins from conception to cancer.FoxO proteins: cunning concepts and considerations for the cardiovascular system.Arginase-II induces vascular smooth muscle cell senescence and apoptosis through p66Shc and p53 independently of its l-arginine ureahydrolase activity: implications for atherosclerotic plaque vulnerability Therapeutic promise and principles: metabotropic glutamate receptors The vitamin nicotinamide: translating nutrition into clinical care.A fork in the path: Developing therapeutic inroads with FoxO proteins.The consequences of mitochondrial amyloid beta-peptide in Alzheimer's disease.Forkhead homeobox type O transcription factors in the responses to oxidative stress.Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress.p66Shc, a multifaceted protein linking Erk signalling, glucose metabolism, and oxidative stress.The Role of p66shc in Oxidative Stress and Apoptosis.Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor.Anthocyanins Protect SK-N-SH Cells Against Acrolein-Induced Toxicity by Preserving the Cellular Redox State.

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P2860

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

http://www.wikidata.org/entity/Q36321606

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

@ast

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

@en

type

label

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

@ast

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

@en

prefLabel

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

@ast

Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

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Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

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Darrell D Norton

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Haibing Jiang

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John W Kusiak

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Nikki J Holbrook

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Shino Nemoto

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Toren Finkel

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Wanli W Smith

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Direct control of the Forkhead transcription factor AFX by protein kinase B

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors

Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

Alzheimer's disease: genes, proteins, and therapy

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

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