Integrins control motile strategy through a Rho-cofilin pathway.
about
alpha v beta3 and alpha5beta1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration.The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes.At the leading edge of three-dimensional cell migrationIntegrin trafficking at a glanceRole of adhesion receptor trafficking in 3D cell migrationMicroglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation.Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectinPersistence of fan-shaped keratocytes is a matrix-rigidity-dependent mechanism that requires α5β1 integrin engagement.β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mousePhactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activityAlpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signallingRandom versus directionally persistent cell migrationInhibition of αvβ3 integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC)PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility.Activation of beta 1 but not beta 3 integrin increases cell traction forces.Effect of RGD functionalization and stiffness modulation of polyelectrolyte multilayer films on muscle cell differentiation.Beta8 integrin binds Rho GDP dissociation inhibitor-1 and activates Rac1 to inhibit mesangial cell myofibroblast differentiation.The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway.Transforming growth factor beta controls the directional migration of hepatocyte cohorts by modulating their adhesion to fibronectin.Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments.NADPH oxidase 1 controls the persistence of directed cell migration by a Rho-dependent switch of alpha2/alpha3 integrins.Kindlin-1 Is required for RhoGTPase-mediated lamellipodia formation in keratinocytesThe membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility.Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces.Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of beta1 integrin.RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complexGOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge.The coordination between actin filaments and adhesion in mesenchymal migration.Integrin beta4 regulates migratory behavior of keratinocytes by determining laminin-332 organizationThe ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration.Proteomic plasma membrane profiling reveals an essential role for gp96 in the cell surface expression of LDLR family members, including the LDL receptor and LRP6.Silencing of miRNA-148a by hypermethylation activates the integrin-mediated signaling pathway in nasopharyngeal carcinomaGenome-wide analysis of three-way interplay among gene expression, cancer cell invasion and anti-cancer compound sensitivity.Beta1 and beta3 integrins cooperate to induce syndecan-4-containing cross-linked actin networks in human trabecular meshwork cellsIntegrin-specific control of focal adhesion kinase and RhoA regulates membrane protrusion and invasion.Effect of bacteria on the wound healing behavior of oral epithelial cells.miR-31 is a broad regulator of β1-integrin expression and function in cancer cells.Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration.Integrins modulate relapse to cocaine-seeking.
P2860
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P2860
Integrins control motile strategy through a Rho-cofilin pathway.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Integrins control motile strategy through a Rho-cofilin pathway.
@ast
Integrins control motile strategy through a Rho-cofilin pathway.
@en
type
label
Integrins control motile strategy through a Rho-cofilin pathway.
@ast
Integrins control motile strategy through a Rho-cofilin pathway.
@en
prefLabel
Integrins control motile strategy through a Rho-cofilin pathway.
@ast
Integrins control motile strategy through a Rho-cofilin pathway.
@en
P2093
P2860
P50
P356
P1476
Integrins control motile strategy through a Rho-cofilin pathway
@en
P2093
Arnoud Sonnenberg
Jacco van Rheenen
Petra Sonneveld
Willeke Franken
P2860
P304
P356
10.1083/JCB.200412081
P407
P577
2005-05-02T00:00:00Z