Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases. - Wikidata - wikimedia - TriplyDB

Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases.

Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases.

http://www.wikidata.org/entity/Q36322834

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Mutational analyses of UPIIIA, SHH, EFNB2 and HNF1beta in persistent cloaca and associated kidney malformations Anatomy and Physiology of the Urinary Tract: Relation to Host Defense and Microbial Infection Glycosylation of uroplakins. Implications for bladder physiopathology Lower urinary tract development and disease Urothelial plaque formation in post-Golgi compartments Intron evolution: testing hypotheses of intron evolution using the phylogenomics of tetraspanins Uroplakins and their potential applications in urology Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouse Tbx18 regulates the development of the ureteral mesenchyme SNX31: a novel sorting nexin associated with the uroplakin-degrading multivesicular bodies in terminally differentiated urothelial cells The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation Cell biology and physiology of the uroepithelium.Alterations in bladder function associated with urothelial defects in uroplakin II and IIIa knockout mice.Assembly of urothelial plaques: tetraspanin function in membrane protein trafficking.All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms.Temporally and spatially controllable gene expression and knockout in mouse urothelium.Hypercompliant apical membranes of bladder umbrella cells.Requirement for a uroplakin 3a-like protein in the development of zebrafish pronephric tubule epithelial cell function, morphogenesis, and polarity Aberrant differentiation of urothelial cells in patients with ureteropelvic junction obstruction.Upk3b is dispensable for development and integrity of urothelium and mesothelium.Claudin-4 deficiency results in urothelial hyperplasia and lethal hydronephrosis.Renal hypoplasia: lessons from Pax2.Uroplakins in the lower urinary tract Uroplakin peptide-specific autoimmunity initiates interstitial cystitis/painful bladder syndrome in mice.Uroplakins in urothelial biology, function, and disease A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4 Molecular basis of renal adaptation in a murine model of congenital obstructive nephropathy.Cytokeratin 15 marks basal epithelia in developing ureters and is upregulated in a subset of urothelial cell carcinomas.The effect of manipulation of silk scaffold fabrication parameters on matrix performance in a murine model of bladder augmentation.Defining protein expression in the urothelium: a problem of more than transitional interest.Autoimmunity to uroplakin II causes cystitis in mice: a novel model of interstitial cystitis.Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions.Kidney adysplasia and variable hydronephrosis, a new mutation affecting the odd-skipped related 1 gene in the mouse, causes variable defects in kidney development and hydronephrosis BALB/c-Fcgr2bPdcd1 mouse expressing anti-urothelial antibody is a novel model of autoimmune cystitis.MAL facilitates the incorporation of exocytic uroplakin-delivering vesicles into the apical membrane of urothelial umbrella cells.Uroplakins do not restrict CO2 transport through urothelium.Lack of evidence for increased level of circulating urothelial cells in the peripheral blood after transurethral resection of bladder tumors.Cellular basis of urothelial squamous metaplasia: roles of lineage heterogeneity and cell replacement Going in circles: conserved mechanisms control radial patterning in the urinary and digestive tracts.Altered phenotype of cultured urothelial and other stratified epithelial cells: implications for wound healing.

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Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases.

http://www.wikidata.org/entity/Q36322834

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Roles of uroplakins in plaque ...... t, and urinary tract diseases.

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Anna B Auerbach

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Bechara Kachar

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Ellen Shapiro

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Fang-Ming Deng

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Feng-Xia Liang

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Ge Zhou

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Nancy Genieser

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Peter K Nelson

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Ping Hu

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Xiang-Tian Kong

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P2860

Mammalian uroplakins. A group of highly conserved urothelial differentiation-related membrane proteins

Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum

Specific tetraspanin functions

Uroplakins Ia and Ib, two major differentiation products of bladder epithelium, belong to a family of four transmembrane domain (4TM) proteins

Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly

LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice

Complexes of tetraspanins with integrins: more than meets the eye

CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system

Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition

Role of membrane proteins in permeability barrier function: uroplakin ablation elevates urothelial permeability

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15611339

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