ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix. - Wikidata - wikimedia - TriplyDB

ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix.

ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix.

http://www.wikidata.org/entity/Q36324827

about

Matrix rigidity regulates cancer cell growth and cellular phenotype.Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth Growth control by intracellular tension and extracellular stiffness Substrate modulus directs neural stem cell behavior Paxillin comes of age Use of three-dimensional collagen gels to study mechanotransduction in T47D breast epithelial cells Focal adhesions, stress fibers and mechanical tension Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities Epithelia migration: a spatiotemporal interplay between contraction and adhesion Mechanical signaling in reproductive tissues: mechanisms and importance From mechanical force to RhoA activation Approaches to manipulating the dimensionality and physicochemical properties of common cellular scaffolds Epithelial machines of morphogenesis and their potential application in organ assembly and tissue engineering Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers Tumor stiffness is unrelated to myosin light chain phosphorylation in cancer cells Composite alginate gels for tunable cellular microenvironment mechanics.A novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1 Growth of human breast tissues from patient cells in 3D hydrogel scaffolds From molecular signal activation to locomotion: an integrated, multiscale analysis of cell motility on defined matrices Cancer cell invasion is enhanced by applied mechanical stimulation Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma.Role of surface chemistry in protein remodeling at the cell-material interface Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration.Environmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor beta Fighting the force: Potential of homeobox genes for tumor microenvironment regulation P190A RhoGAP is required for mammary gland development β-Adrenergic inhibition of contractility in L6 skeletal muscle cells Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression The extracellular matrix: a dynamic niche in cancer progression Integrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective.Tissue stiffness dictates development, homeostasis, and disease progression.Matrix microarchitecture and myosin II determine adhesion in 3D matrices.Focal adhesion kinase as a regulator of cell tension in the progression of cancer.Substrate rigidity regulates the formation and maintenance of tissues.Rho kinase, myosin-II, and p42/44 MAPK control extracellular matrix-mediated apical bile canalicular lumen morphogenesis in HepG2 cells.Collagen reorganization at the tumor-stromal interface facilitates local invasion.Determining the mechanical properties of human corneal basement membranes with atomic force microscopy Collagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matrices Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells.A photo-modulatable material for probing cellular responses to substrate rigidity.

P2860

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P2860

ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix.

http://www.wikidata.org/entity/Q36324827

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

ROCK-generated contractility r ...... e-dimensional collagen matrix.

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ROCK-generated contractility r ...... e-dimensional collagen matrix.

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ROCK-generated contractility r ...... e-dimensional collagen matrix.

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ROCK-generated contractility r ...... e-dimensional collagen matrix.

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ROCK-generated contractility r ...... e-dimensional collagen matrix.

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Journal of Cell Biology

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ROCK-generated contractility r ...... e-dimensional collagen matrix.

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P2093

Channing J Der

http://www.w3.org/2001/XMLSchema#string

Michele A Wozniak

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Patricia A Solski

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Patricia J Keely

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Radhika Desai

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P2860

Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

R-Ras promotes focal adhesion formation through focal adhesion kinase and p130(Cas) by a novel mechanism that differs from integrins.

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

P190-B, a Rho-GTPase-activating protein, is differentially expressed in terminal end buds and breast cancer

Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase

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10.1083/JCB.200305010

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14610060

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2173660

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