Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death
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No death without life: vital functions of apoptotic effectorsTranscription factors in late megakaryopoiesis and related platelet disordersApoptosis: role in myeloid cell developmentIL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs.Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiationA novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentationMechanisms of organelle transport and capture along proplatelets during platelet production.Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cellsA ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis.The biogenesis of platelets from megakaryocyte proplatelets.CD8+ T cells suppress autologous megakaryocyte apoptosis in idiopathic thrombocytopenic purpura.15-deoxy-delta12,14-PGJ2 enhances platelet production from megakaryocytes.Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets.A megakaryocyte with no platelets: anti-platelet antibodies, apoptosis, and platelet production.The role of apoptosis in megakaryocytes and platelets.Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation.Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.Mitoquinone restores platelet production in irradiation-induced thrombocytopenia.Interspecies Variation in the Functional Consequences of Mutation of Cytochrome cRegulation of platelet lifespan by apoptosis.Slowed decay of mRNAs enhances platelet specific translationProplatelet formation of megakaryocytes is triggered by autocrine-synthesized estradiol.Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells.The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-κB inhibition.Actin inhibition increases megakaryocyte proplatelet formation through an apoptosis-dependent mechanism.Megakaryocyte apoptosis: sorting out the signalsProposed megakaryocytic regulon of p53: the genes engaged to control cell cycle and apoptosis during megakaryocytic differentiation.The bone marrow vascular niche: home of HSC differentiation and mobilization.Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake.Megakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction.Sepsis alters the megakaryocyte-platelet transcriptional axis resulting in granzyme B-mediated lymphotoxicity.Platelets: developmental biology, physiology, and translatable platforms for preclinical investigation and drug development.Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets.The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease.In vitro megakaryocyte production and platelet biogenesis: state of the artEx vivo production of platelets from stem cells.Anaplasma phagocytophilum infection modulates expression of megakaryocyte cell cycle genes through phosphatidylinositol-3-kinase signalingProplatelet formation in megakaryocytes is associated with endoplasmic reticulum stress.Thrombin Maybe Plays an Important Role in MK Differentiation into Platelets.
P2860
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P2860
Compartmentalized megakaryocyte death generates functional platelets committed to caspase-independent death
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Compartmentalized megakaryocyt ...... d to caspase-independent death
@ast
Compartmentalized megakaryocyt ...... d to caspase-independent death
@en
type
label
Compartmentalized megakaryocyt ...... d to caspase-independent death
@ast
Compartmentalized megakaryocyt ...... d to caspase-independent death
@en
prefLabel
Compartmentalized megakaryocyt ...... d to caspase-independent death
@ast
Compartmentalized megakaryocyt ...... d to caspase-independent death
@en
P2093
P2860
P356
P1476
Compartmentalized megakaryocyt ...... d to caspase-independent death
@en
P2093
Brendon S Noble
David B Jones
John Savill
Simon B Brown
P2860
P304
P356
10.1083/JCB.200210111
P407
P577
2003-02-01T00:00:00Z