FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest.
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Normal proliferation and differentiation of Hoxc-8 transgenic chondrocytes in vitroFibroblast growth factor signaling in skeletal development and diseasePP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues.Pocket proteins and cell cycle controlTissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130Regulation of neuron survival and death by p130 and associated chromatin modifiers.FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescencePP2A-mediated dephosphorylation of p107 plays a critical role in chondrocyte cell cycle arrest by FGFNew insight on FGFR3-related chondrodysplasias molecular physiopathology revealed by human chondrocyte gene expression profilingLoss of the mammalian DREAM complex deregulates chondrocyte proliferationp107 in the public eye: an Rb understudy and more.Differential gene expression of the intermediate and outer interzone layers of developing articular cartilage in murine embryos.Genetic determinants of phosphate response in Drosophila.Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation.Cooperation between p27 and p107 during endochondral ossification suggests a genetic pathway controlled by p27 and p130.A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation.The Indispensable Role of Cyclin-Dependent Kinase 1 in Skeletal Development.FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth.Cell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP.Activation of p107 by fibroblast growth factor, which is essential for chondrocyte cell cycle exit, is mediated by the protein phosphatase 2A/B55α holoenzyme.Swarm chondrosarcoma: a continued resource for chondroblastic-like extracellular matrix and chondrosarcoma biology research.Phosphoproteomics of Fibroblast Growth Factor 1 (FGF1) Signaling in Chondrocytes: Identifying the Signature of Inhibitory Response.Achondroplasia: Development, pathogenesis, and therapy.The B55α regulatory subunit of protein phosphatase 2A mediates fibroblast growth factor-induced p107 dephosphorylation and growth arrest in chondrocytes.Overexpression of cyclin E/CDK2 complexes overcomes FGF-induced cell cycle arrest in the presence of hypophosphorylated Rb proteinsFGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G₂arrest in RCS chondrocytes.Disruption of calvarial ossification in E2f4 mutant embryos correlates with increased proliferation and progenitor cell populations.Altered signaling in the G1 phase deregulates chondrocyte growth in a mouse model with proteoglycan undersulfation.
P2860
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P2860
FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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name
FGF signaling targets the pRb- ...... uce chondrocyte growth arrest.
@ast
FGF signaling targets the pRb- ...... uce chondrocyte growth arrest.
@en
type
label
FGF signaling targets the pRb- ...... uce chondrocyte growth arrest.
@ast
FGF signaling targets the pRb- ...... uce chondrocyte growth arrest.
@en
prefLabel
FGF signaling targets the pRb- ...... uce chondrocyte growth arrest.
@ast
FGF signaling targets the pRb- ...... uce chondrocyte growth arrest.
@en
P2093
P2860
P356
P1476
FGF signaling targets the pRb- ...... uce chondrocyte growth arrest.
@en
P2093
Claudio Basilico
Emmanuel Laplantine
Ferdinand Rossi
Malika Sahni
P2860
P304
P356
10.1083/JCB.200205025
P407
P577
2002-08-12T00:00:00Z