Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells.
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Mammalian lipoxygenases and their biological relevance12- and 15-lipoxygenases in adipose tissue inflammationInducible endothelium-derived hyperpolarizing factor: role of the 15-lipoxygenase-EDHF pathwayFunctional and pathological roles of the 12- and 15-lipoxygenasesAberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis modelRole of 12-lipoxygenase in hypoxia-induced rat pulmonary artery smooth muscle cell proliferationEffects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAsRegulation of renal 12(S)-hydroxyeicosatetraenoic acid in diabetes by angiotensin AT1 and AT2 receptorsEvidence that increased 12-lipoxygenase activity induces apoptosis in fibroblasts.The effects of leukocyte-type 12/15-lipoxygenase on Id3-mediated vascular smooth muscle cell growth.12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in miceIL-8/CXCL8 Upregulates 12-Lipoxygenase Expression in Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats.Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLCPathological aspects of lipid peroxidation.12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets.Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization.Products of 12/15-lipoxygenase upregulate the angiotensin II receptor.Eicosanoids, β-cell function, and diabetesCatalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activationDisparate effects of 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid in vascular endothelial and smooth muscle cells and in cardiomyocytes.Role of lipoxygenase products in the effects of angiotensin II in the isolated aorta and perfused heart of the rat.Lipid peroxidation and decomposition--conflicting roles in plaque vulnerability and stability.Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetesRegulation of Vascular Smooth Muscle Cell Dysfunction Under Diabetic Conditions by miR-504Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism.MicroRNAs and their role in progressive kidney diseases.Hyperglycemia in aneurysmal subarachnoid hemorrhage: a potentially modifiable risk factor for poor outcome.The role of mid-chain hydroxyeicosatetraenoic acids in the pathogenesis of hypertension and cardiac hypertrophy.P450 Eicosanoids and Reactive Oxygen Species Interplay in Brain Injury and Neuroprotection.Targeting of 12/15-Lipoxygenase in retinal endothelial cells, but not in monocytes/macrophages, attenuates high glucose-induced retinal leukostasis.Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction.Angiotensin II increases macrophage-mediated modification of low density lipoprotein via a lipoxygenase-dependent pathway.Mechanisms of ANG II-induced mitogenic responses: role of 12-lipoxygenase and biphasic MAP kinase.A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: role of glucose and 12-hydroxyeicosatetraenoic acid.Temporal Changes in Skeletal Muscle Capillary Responses and Endothelial-Derived Vasodilators in Obesity-Related Insulin Resistance.Inhibition of 12/15-Lipoxygenase Reduces Renal Inflammation and Injury in Streptozotocin-Induced Diabetic Mice.Comparison of 12-lipoxygenase expression in vascular smooth muscle cells from old normotensive Wistar-Kyoto rats with spontaneously hypertensive rats.The oxidized lipid and lipoxygenase product 12(S)-hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angioten
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P2860
Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Elevated glucose and angiotens ...... ne aortic smooth muscle cells.
@ast
Elevated glucose and angiotens ...... ne aortic smooth muscle cells.
@en
type
label
Elevated glucose and angiotens ...... ne aortic smooth muscle cells.
@ast
Elevated glucose and angiotens ...... ne aortic smooth muscle cells.
@en
prefLabel
Elevated glucose and angiotens ...... ne aortic smooth muscle cells.
@ast
Elevated glucose and angiotens ...... ne aortic smooth muscle cells.
@en
P2093
P2860
P356
P1476
Elevated glucose and angiotens ...... ne aortic smooth muscle cells.
@en
P2093
N Gonzales
R Natarajan
P2860
P304
P356
10.1073/PNAS.90.11.4947
P407
P577
1993-06-01T00:00:00Z