MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
about
Sanguinarine inhibits growth and invasion of gastric cancer cells via regulation of the DUSP4/ERK pathway.Decreased expression of miR-939 contributes to chemoresistance and metastasis of gastric cancer via dysregulation of SLC34A2 and Raf/MEK/ERK pathway.Modulation of Ras/ERK and Phosphoinositide Signaling by Long-Chain n-3 PUFA in Breast Cancer and Their Potential Complementary Role in Combination with Targeted Drugs.The selective c-Met inhibitor tepotinib can overcome epidermal growth factor receptor inhibitor resistance mediated by aberrant c-Met activation in NSCLC models.Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors.Synthetic lethal interaction of cetuximab with MEK1/2 inhibition in NRAS-mutant metastatic colorectal cancer.Structure-Guided Design and Initial Studies of a Bifunctional MEK/PI3K Inhibitor (ST-168).A cellular threshold for active ERK1/2 levels determines Raf/MEK/ERK-mediated growth arrest versus death responses.Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model.
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Q33684181-01EE2E00-A597-4177-9AEB-F04A9E9C409CQ37602508-087C56B1-879C-4BFA-9221-67781C3A22CFQ37729599-C337F49C-A8A1-4A33-A155-B4C79372BAC0Q38704952-A78C0029-7D6C-4CF7-A9BC-BE6EE05B20C8Q41249331-EAED9922-FCE4-493C-A2E2-21F12681F0AFQ42316814-77E281F3-4A1A-414C-B10E-428C6B4A17CEQ47760790-6294A105-CA5A-4D86-97BE-CB38F621F558Q47848122-707421FF-A119-4FB4-8294-0FD150B8AFBDQ49952320-BF6CD897-0A08-4E6D-9E7C-B6A67006F443
P2860
MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
@ast
MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
@en
type
label
MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
@ast
MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
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prefLabel
MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
@ast
MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
@en
P2860
P1433
P1476
MEK1/2 Inhibitors: Molecular Activity and Resistance Mechanisms.
@en
P2093
Jong-In Park
Pui-Kei Wu
P2860
P304
P356
10.1053/J.SEMINONCOL.2015.09.023
P577
2015-09-24T00:00:00Z