Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis - Wikidata - wikimedia - TriplyDB

Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis

Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis

http://www.wikidata.org/entity/Q36330655

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Fibroblasts and myofibroblasts in wound healing The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis Molecular imaging of integrin αvβ6 expression in living subjects.αv integrins: key regulators of tissue fibrosis Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1.Grape seed pro-anthocyanidins ameliorates radiation-induced lung injury.New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses.Pathobiology of liver fibrosis: a translational success story Long intergenic non-coding RNA induced by X-ray irradiation regulates DNA damage response signaling in the human bronchial epithelial BEAS-2B cell line Genomic meta-analysis of growth factor and integrin pathways in chronic kidney transplant injury Radiation-induced impairment in lung lymphatic vasculature Pharmacological induction of transforming growth factor-beta1 in rat models enhances radiation injury in the intestine and the heart Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.Type V collagen induced tolerance suppresses collagen deposition, TGF-β and associated transcripts in pulmonary fibrosis TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment.Role of von Hippel-Lindau protein in fibroblast proliferation and fibrosis Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12.Biological Significance of Local TGF-β Activation in Liver Diseases.Radiation-induced fibrosis: mechanisms and implications for therapy Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis BARD1 mediates TGF-β signaling in pulmonary fibrosis.Molecular and cellular mechanisms of pulmonary fibrosis.Current and novel drug therapies for idiopathic pulmonary fibrosis.Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity.Expression of Angiotensin II and Aldosterone in Radiation-induced Lung Injury.Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis.TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now?Choreographing metastasis to the tune of LTBP.Expression of integrin alphavbeta6 and TGF-beta in scarless vs scar-forming wound healing.Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins.Biologically conformal treatment: biomarkers and functional imaging in radiation oncology.What the lung has taught us about latent TGF-beta activation.Antitransforming growth factor-beta therapy in fibrosis: recent progress and implications for systemic sclerosis.Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders.Transforming growth factor beta as a therapeutic target in systemic sclerosis.

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Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis

http://www.wikidata.org/entity/Q36330655

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2007 nî lūn-bûn

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2007年學術文章

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RCCM.200706-806OC

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American Journal of Respiratory and Critical Care Medicine

P1476

Inhibition of integrin alpha(v ...... adiation-induced lung fibrosis

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Cristina Colarossi

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Emmanuel Bayongan

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Gerald S Horan

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Khalid Puthawala

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Kristen S Grant

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Mary Louise Devitt

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Matvey E Lukashev

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Nicos Hadjiangelis

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Shelia M Violette

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Silvia C Formenti

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P2860

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin

The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1

Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity

The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis

Activation of latent TGF-beta by thrombospondin-1: mechanisms and physiology

Making sense of latent TGFbeta activation

TGF-beta is a critical mediator of acute lung injury

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

TGF-beta and fibrosis.

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82-90

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10.1164/RCCM.200706-806OC

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1

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177

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Paul H. Weinreb

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2007-10-04T00:00:00Z

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17916808

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pulmonary fibrosis

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2176115

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