Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor. - Wikidata - wikimedia - TriplyDB

Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor.

Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor.

http://www.wikidata.org/entity/Q36331374

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Structural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase disease Regulation of ERBB3/HER3 signaling in cancer The MADD-3 LAMMER Kinase Interacts with a p38 MAP Kinase Pathway to Regulate the Display of the EVA-1 Guidance Receptor in Caenorhabditis elegans Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor Cloning and characterisation of Schistosoma japonicum insulin receptors Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B Computational delineation of tyrosyl-substrate recognition and catalytic landscapes by the epidermal growth factor receptor tyrosine kinase domain.Characterization of a eukaryotic-like tyrosine protein kinase expressed by the Shiga toxin-encoding bacteriophage 933W A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1 Identification of csk tyrosine phosphorylation sites and a tyrosine residue important for kinase domain structure.A kinase-negative epidermal growth factor receptor that retains the capacity to stimulate DNA synthesis Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity.Targeting HER2 Positive Breast Cancer with Chemopreventive Agents.Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation A conserved helix motif complements the protein kinase core.Modulation of erbB kinase activity and oncogenic potential by single point mutations in the glycine loop of the catalytic domain.Signalling through kinase-defective domains: the prevalence of atypical receptor-like kinases in plants.Structural analysis of p185c-neu and epidermal growth factor receptor tyrosine kinases: oligomerization of kinase domains An investigation of the role of Glu-842, Glu-844 and His-846 in the function of the cytoplasmic domain of the epidermal growth factor receptor.Mutagenic structure/function analysis of the cytoplasmic cysteines of the insulin receptor.Identification and characterization of tyrosine kinases in anole lizard indicate the conserved tyrosine kinase repertoire in vertebrates.Nrdp1-mediated ErbB3 degradation inhibits glioma cell migration and invasion by reducing cytoplasmic localization of p27(Kip1).EGFR kinase possesses a broad specificity for ErbB phosphorylation sites, and ligand increases catalytic-centre activity without affecting substrate binding affinity.EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain.Mutational analysis of the nucleotide binding site of the epidermal growth factor receptor and v-Src protein-tyrosine kinases.Two sequences flanking the major autophosphorylation site of the insulin receptor are essential for tyrosine kinase activation.Substrate recognition by casein kinase-II: the role of histidine-160.cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer The direct activation of MIK, a germinal center kinase (GCK)-like kinase, by MARK, a maize atypical receptor kinase, suggests a new mechanism for signaling through kinase-dead receptors.Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition.

P2860

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P2860

Structural features that specify tyrosine kinase activity deduced from homology modeling of the epidermal growth factor receptor.

http://www.wikidata.org/entity/Q36331374

description

1993 nî lūn-bûn

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1993年の論文

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1993年学术文章

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1993年学术文章

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1993年学术文章

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1993年学术文章

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1993年学术文章

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1993年學術文章

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1993年學術文章

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1993年學術文章

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Structural features that speci ...... dermal growth factor receptor.

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Structural features that speci ...... dermal growth factor receptor.

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PNAS.90.11.5001

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Proceedings of the National Academy of Sciences of the United States of America

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Structural features that speci ...... dermal growth factor receptor.

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D L Cadena

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D R Knighton

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G N Gill

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J M Sowadski

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J Zheng

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L F Ten Eyck

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S S Taylor

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P2860

Enzyme-Catalyzed Phosphoryl Transfer Reactions

A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators

Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors

The relation between the divergence of sequence and structure in proteins

Molecular cloning and expression of an additional epidermal growth factor receptor-related gene

Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

Refined structure of porcine cytosolic adenylate kinase at 2.1 A resolution

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution

Structure of holo-glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus at 1.8 A resolution

Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution

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8389462

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