Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation
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Highlights on distinctive structural and functional properties of HTLV Tax proteinsNF-kappaB activation: Tax sumoylation is out, but what about Tax ubiquitination?HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin ChainsTax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.A non-SUMOylated tax protein is still functional for NF-κB pathway activation.HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.The importance of ubiquitination and sumoylation on the transforming activity of HTLV Tax-1 and Tax-2.Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein.The cellular autophagy pathway modulates human T-cell leukemia virus type 1 replication.Acetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast modelRegulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.Tax posttranslational modifications and interaction with calreticulin in MT-2 cells and human peripheral blood mononuclear cells of human T cell lymphotropic virus type-I-associated myelopathy/tropical spastic paraparesis patients.The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-κB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein.Tax secretion from peripheral blood mononuclear cells and Tax detection in plasma of patients with human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis and asymptomatic carriers.Viral Interplay with the Host Sumoylation System.Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.HTLV Deregulation of the NF-κB Pathway: An Update on Tax and Antisense Proteins Role.
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P2860
Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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2012年學術文章
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name
Low nuclear body formation and ...... NF-kappaB promoter activation
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Low nuclear body formation and ...... NF-kappaB promoter activation
@en
type
label
Low nuclear body formation and ...... NF-kappaB promoter activation
@ast
Low nuclear body formation and ...... NF-kappaB promoter activation
@en
prefLabel
Low nuclear body formation and ...... NF-kappaB promoter activation
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Low nuclear body formation and ...... NF-kappaB promoter activation
@en
P2093
P2860
P50
P356
P1433
P1476
Low nuclear body formation and ...... NF-kappaB promoter activation
@en
P2093
Laetitia Waast
Laurence Bénit
Martine Nedelec
Patrycja Nzounza
Sabrina Pene
Voahangy Randrianarison-Huetz
P2860
P2888
P356
10.1186/1742-4690-9-77
P577
2012-09-25T00:00:00Z
P5875
P6179
1036775900