Understanding the longevity of the beta-lactam antibiotics and of antibiotic/beta-lactamase inhibitor combinations.
about
Three decades of beta-lactamase inhibitorsDesign, Synthesis, and Crystal Structures of 6-Alkylidene-2′-Substituted Penicillanic Acid Sulfones as Potent Inhibitors of Acinetobacter baumannii OXA-24 CarbapenemaseInsight into the effect of inhibitor resistant S130G mutant on physico-chemical properties of SHV type beta-lactamase: a molecular dynamics studyKinetics and mechanism of inhibition of a serine beta-lactamase by O-aryloxycarbonyl hydroxamatesGenes involved in intrinsic antibiotic resistance of Acinetobacter baylyi.Escherichia coli genes that reduce the lethal effects of stress.Structural and Functional Aspects of Class A Carbapenemases.Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase.Substituted aryl malonamates as new serine beta-lactamase substrates: structure-activity studiesThe role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.Antibiotic sensitivity profiles determined with an Escherichia coli gene knockout collection: generating an antibiotic bar code.Intramolecular cooperativity in the reaction of diacyl phosphates with serine beta-lactamasesInhibition of class A and C beta-lactamases by diaroyl phosphates.Synergistic interactions of vancomycin with different antibiotics against Escherichia coli: trimethoprim and nitrofurantoin display strong synergies with vancomycin against wild-type E. coliSyntheses and studies of new forms of N-sulfonyloxy β-lactams as potential antibacterial agents and β-lactamase inhibitors.Determination of antibiotic hypersensitivity among 4,000 single-gene-knockout mutants of Escherichia coliKinetics and stereochemistry of hydrolysis of an N-(phenylacetyl)-α-hydroxyglycine ester catalyzed by serine β-lactamases and DD-peptidases.The intrinsic resistome of bacterial pathogens.Structural and mechanistic insights into the inhibition of class C β-lactamases through the adenylylation of the nucleophilic serine.Deoxycytidine deaminase-deficient Escherichia coli strains display acute sensitivity to cytidine, adenosine, and guanosine and increased sensitivity to a range of antibiotics, including vancomycin.Structural basis for the extended substrate spectrum of AmpC BER and structure-guided discovery of the inhibition activity of citrate against the class C β-lactamases AmpC BER and CMY-10.Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfoneIn vitro and in vivo properties of BAL30376, a β-lactam and dual beta-lactamase inhibitor combination with enhanced activity against Gram-negative Bacilli that express multiple β-lactamasesGMP and IMP Are Competitive Inhibitors of CMY-10, an Extended-Spectrum Class C β-LactamaseStudies on the chemistry and reactivity of alpha-substituted ketones in isonitrile-based multicomponent reactionsAlkylidene Oxapenem β-Lactamase Inhibitors Revisited: Potent Broad Spectrum Activity but New Stability Challenges.Inhibition of a cold-active alkaline phosphatase by imipenem revealed by in silico modeling of metallo-β-lactamase active sites.Tackling the Antibiotic Resistance Caused by Class A -Lactamases through the Use of -Lactamase Inhibitory Protein
P2860
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P2860
Understanding the longevity of the beta-lactam antibiotics and of antibiotic/beta-lactamase inhibitor combinations.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
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2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
@zh-hant
name
Understanding the longevity of ...... tamase inhibitor combinations.
@ast
Understanding the longevity of ...... tamase inhibitor combinations.
@en
type
label
Understanding the longevity of ...... tamase inhibitor combinations.
@ast
Understanding the longevity of ...... tamase inhibitor combinations.
@en
prefLabel
Understanding the longevity of ...... tamase inhibitor combinations.
@ast
Understanding the longevity of ...... tamase inhibitor combinations.
@en
P1476
Understanding the longevity of ...... tamase inhibitor combinations.
@en
P2093
John D Buynak
P304
P356
10.1016/J.BCP.2005.11.012
P407
P577
2005-12-13T00:00:00Z