Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony-stimulating factor on the basis of Lyt-2 phenotype
about
Influence of activating stimulus on functional phenotype: interleukin 2 mRNA accumulation differentially induced by ionophore and receptor ligands in subsets of murine T cells.Perforin is present only in normal activated Lyt2+ T lymphocytes and not in L3T4+ cells, but the serine protease granzyme A is made by both subsets.Functional characterization of an antigen involved in an early step of T-cell activation.Precursors of T cell growth factor producing cells in the thymus: ontogeny, frequency, and quantitative recovery in a subpopulation of phenotypically mature thymocytes defined by monoclonal antibody GK-1.5.Activated B cells express receptors for, and proliferate in response to, pure interleukin 2.Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell function.Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chainHeterogeneity in lymphokine profiles of CD4+ and CD8+ T cells and clones activated in vivo and in vitro.Spontaneous release of interleukin 2 by lung T lymphocytes in active pulmonary sarcoidosis is primarily from the Leu3+DR+ T cell subsetRole of alveolar macrophage- and lung T cell-derived mediators in pulmonary sarcoidosis.IgG1 induction factor.Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen-reactivity.Regulation of Ig class secretion by soluble products of certain T-cell lines.Fate of T-lymphocyte injected into immunodeficient allogeneic nude or semi-allogeneic F1 mice: correlation with manifestations of graft-versus-host reaction.Immune-interferon (IFN-gamma), macrophage-activating factors (MAFs), and colony-stimulating factors (CSFs) secreted by T cell clones in limiting dilution microcultures, long-term cultures, and by T cell hybridomas.Limiting dilution analysis of the response of murine L3T4+ spleen cells to alloantigen.Cytotoxic T cells both produce and respond to interleukin 2.Detection of individual interleukin 4- and gamma interferon-producing murine spleen cells after activation with T-cell mitogens.A model of T cell-target interaction leading to lymphokine release.
P2860
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P2860
Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony-stimulating factor on the basis of Lyt-2 phenotype
description
1982 nî lūn-bûn
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1982年の論文
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1982年学术文章
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1982年学术文章
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1982年学术文章
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1982年学术文章
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1982年學術文章
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1982年學術文章
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name
Precursor frequency analysis o ...... n the basis of Lyt-2 phenotype
@ast
Precursor frequency analysis o ...... n the basis of Lyt-2 phenotype
@en
type
label
Precursor frequency analysis o ...... n the basis of Lyt-2 phenotype
@ast
Precursor frequency analysis o ...... n the basis of Lyt-2 phenotype
@en
prefLabel
Precursor frequency analysis o ...... n the basis of Lyt-2 phenotype
@ast
Precursor frequency analysis o ...... n the basis of Lyt-2 phenotype
@en
P2860
P356
P1476
Precursor frequency analysis o ...... n the basis of Lyt-2 phenotype
@en
P2093
H R Macdonald
P2860
P304
P356
10.1084/JEM.156.5.1366
P407
P50
P577
1982-11-01T00:00:00Z